GABA Receptors

20 个项目

每页

设置降序顺序
  1. Muscimol hydrobromide

    Catalog No. A13459
    Quick View
    GABA(A) receptor 激动剂
    Muscimol hydrobromide是抗抑郁药氟西汀的活性代谢产物,可抑制5-羟色胺的摄取,pKi值为7.35.1。诺氟西汀的S-对映体的5-羟色胺再摄取阻断效能比R-对映体高20倍(分别为pKis = 7.86与6.51)。 了解更多
  2. Piperazine

    Catalog No. A16171
    Quick View
    GABA receptor 激动剂
    Piperazine是由六元环组成的有机化合物,该六元环在环的相对位置包含两个氮原子。 了解更多
  3. Bamaluzole

    Catalog No. A17107
    Quick View
    GABA receptor 激动剂
    Bamaluzole是GABA受体激动剂。 了解更多
  4. Afloqualone

    Catalog No. A17276
    Quick View
    GABA receptor agonist
    Afloqualone, also known as HQ-495, is a centrally acting muscle relaxant. Afloqualone inhibits vestibular nystagmus probably due to both inhibition of selective polysynaptic transmission and enhancement of the effects of GABA and glycine in the lateral vestibular nucleus (LVN), and its GABA-enhancing effect is thought to be attributable to the increased sensitivity of GABA receptors of the LVN neuron site. 了解更多
  5. Homotaurine

    Catalog No. A17944
    Quick View
    GABA receptor agonist
    Tramiprosate, also known as homotaurine, is a gamma-Aminobutyric acid (GABA) receptor agonist and a glycosaminoglycan mimetic used in the treatment of Alzheimer's disease. 了解更多
  6. Baclofen

    Catalog No. A18248
    Quick View
    GABA agonist
    Baclofen is a GABA agonist specific for GABA-B receptors. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission. 了解更多
  7. a5IA

    Catalog No. A14343
    Quick View
    Benzodiazepine 激动剂
    a5IA是促智药物,它在GABAA受体的苯并二氮杂卓结合位点上起亚型选择性反向激动剂的作用。 了解更多
  8. Bretazenil

    Catalog No. A13784
    Quick View
    GABAA 激动剂
    Bretazenil,苯二氮卓类受体局部激动剂,可预防OP中毒。 了解更多
  9. AWD 131-138

    Catalog No. A13726
    Quick View
    GABAA receptor 激动剂
    AWD 131-138是一种新的低亲和力的部分苯二氮卓类受体激动剂,在啮齿动物模型中具有强大的抗惊厥和抗焦虑特性。 了解更多
  10. Gaboxadol hydrochloride

    Catalog No. A21730
    Quick View
    GABAA receptors agonist
    Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects. 了解更多
  11. THIP

    Catalog No. A21738
    Quick View
    δ-GABAAR agonist
    THIP (Gaboxadol) is a selective δ-aminobutyric acid type A receptor (δ-GABAAR) agonist. 了解更多
  12. CP-409092 hydrochloride

    Catalog No. A21397
    Quick View
    GABAA receptor partial agonist
    CP-409092 hydrochloride is a partial agonist of GABAA receptor, with anti-anxiety activity. 了解更多
  13. L-655708

    Catalog No. A21181
    Quick View
    GABAA receptor inverse agonist
    L-655708 is a potent α5 subunit-selective GABAA receptor inverse agonist (Ki = 0.45 nM). 了解更多
  14. (R)-Baclofen

    Catalog No. A16680
    Quick View
    GABAB receptor agonist
    (R)-Baclofen(STX209) is a selective GABAB receptor agonist. 了解更多
  15. U-101017

    Catalog No. A13357
    Quick View
    Benzodiazepine receptor/GABAA receptor agonist
    U-101017 is a partial agonist of benzodiazepine receptor and GABAA receptor, with anxiolytic effects. 了解更多
  16. Acamprosate calcium

    Catalog No. A11308
    Quick View
    GABA receptor agonist
    Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction. 了解更多
  17. MRK-016

    Catalog No. A12046
    Quick View
    GABAA α5 receptor agonist
    MRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77?and 1.4?nM for human?GABAA?α1β3γ2, GABAA?α2β3γ2, GABAA?α3β3γ2, and GABAA?α5β3γ2, respectively; MRK-016 also readily penetrates the CNS. 了解更多
  18. RWJ-51204

    Catalog No. A12875
    Quick View
    partial agonist of GABA(A) receptor
    RWJ-51204 is a partial agonist of GABA(A) receptor, with Ki of 0.2-2 nM to the benzodiazepine site on GABA(A) receptors. 了解更多
  19. TPA 023

    Catalog No. A20140
    Quick View
    GABAA α2/α3 agonist
    TPA 023 is a GABAA α2/α3 subtype-selective agonist, with Ki of 0.19-0.41 nM. 了解更多
  20. CP-409092

    Catalog No. A20152
    Quick View
    GABAA receptor partial agonist
    CP-409092 is a partial agonist of GABAA receptor, with anti-anxiety activity. 了解更多

20 个项目

每页

设置降序顺序
Rewards