GPCR19
GPCR19 (GPBA receptors, TGR5, GPBAR1, M-BAR) are G protein-coupled receptors (GPCRs) that are activated by bile acids. They are highly expressed in the gallbladder, ileum, and colon, and are important in the regulation of glucose and lipid metabolism, and energy utilization. Diseases associated with GPBAR1 include Sclerosing Cholangitis and Intrahepatic Cholestasis Of Pregnancy. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and G protein-coupled bile acid receptor activity.
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INT-777
Catalog No. A21168 -
TGR5-Receptor-Agonist
Catalog No. A13732 TGR5(GPCR19) 激动剂TGR5 Receptor Agonist是一种有效的TGR5(GPCR19)激动剂,在U2-OS细胞分析(pEC50 = 6.8)和黑素细胞(pEC50 = 7.5)中显示出增强的效力。 了解更多