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使用 'CFTR' 作为标签的产品

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CFTR-Inhibitor-II

Catalog No. A13723
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CFTR 抑制剂

CFTR inhibitor II,也称为GlyH-101，是一种甘氨酸酰肼，可选择性和可逆地阻断CFTR通道（Ki = 4.3 uM）。了解更多

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- Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
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CFTRinh-172

Catalog No. A12897
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CFTR 抑制剂

CFTRinh-172是电压无关的选择性CFTR抑制剂。在2分钟内可逆地抑制CFTR短路电流的 Ki 值为300 nM。了解更多

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- Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
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IOWH032

Catalog No. A13511
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CFTR 抑制剂

IOWH032是CFTR抑制剂。了解更多

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PTC124 (Ataluren)

Catalog No. A10758
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CFTR 抑制剂

PTC124也称为Ataluren，是CFTR-G542X无意义等位基因抑制剂。了解更多

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- L Kadunc, .et al. Increased Gene Translation Stringency in Mammalian Cells by Nonsense Suppression at Multiple Permissive Sites With a Single Noncanonical Amino Acid, FEBS Lett, 2020, May 13 PMID: 32401336
- Caspi M, .et al. A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents, J Mol Med (Berl), 2016, Apr;94(4):469-82 PMID: 26620677

Adooq Bioscience

使用 'CFTR' 作为标签的产品

CFTR-Inhibitor-II

CFTRinh-172

IOWH032

PTC124 (Ataluren)

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