Microbiology

产品 51 到 100 共 245个

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  1. Balapiravir (R1626)

    Catalog No. A11335
    Polymerase 抑制剂
    Balapiravir (R1626)是丙型肝炎病毒(HCV) RNA依赖性rna聚合酶(R1479,RG1479)核苷类似物抑制剂的前药。 了解更多
  2. BMS-790052 2HCl

    Catalog No. A11336
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    NS5A 抑制剂
    BMS-790052 2HCl是一种NS5A抑制剂,用于治疗丙型肝炎病毒(HCV)感染。 了解更多
  3. Ciluprevir (BILN 2061)

    Catalog No. A11343
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    HCV NS3 protease 抑制剂
    Ciluprevir (BILN 2061)是HCV NS3蛋白酶的一种特定而有效的拟肽抑制剂。 了解更多
  4. PSI-6130

    Catalog No. A11519
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    HCV Nucleoside 抑制剂
    PSI-6130是丙型肝炎病毒核苷抑制剂。 了解更多
  5. Tegobuvir (GS-9190)

    Catalog No. A11583
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    NS5B polymerase 抑制剂
    Tegobuvir (GS-9190)是一种非核苷NS5B聚合酶抑制剂。 了解更多
  6. VCH-916

    Catalog No. A12374
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    HCV NS5B polymerase 抑制剂
    VCH-916是一种新型非核苷HCV NS5B聚合酶抑制剂。 了解更多
  7. Setrobuvir (ANA-598)

    Catalog No. A13105
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    HCV Polymerase 抑制剂
    Setrobuvir (ANA-598)是一种直接作用的抗病毒药物或DAA,是HCV RNA聚合酶的一种非核苷抑制剂。 了解更多
  8. Celgosivir

    Catalog No. A13118
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    alpha-glucosidase I 抑制剂
    Celgosivir是一种用于潜在治疗HCV感染的α-葡萄糖苷酶I抑制剂。 了解更多
  9. Ledipasvir (GS 5885)

    Catalog No. A13155
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    NS5A 抑制剂
    Ledipasvir (GS 5885)是丙型肝炎病毒HCV NS5A蛋白的抑制剂。 了解更多
  10. PSI-7977

    Catalog No. A11529
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    HCV Nucleotide 抑制剂
    PSI-7977是PSI-7851的氨基磷酸酯前药,PSI-7851是核苷类似物,当磷酸化时,抑制丙型肝炎病毒的RNA依赖性RNA聚合酶(EC50 = 92 nM)。 了解更多
  11. PSI-6206

    Catalog No. A11530
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    HCV RNA polymerase 抑制剂
    PSI-6206是PSI-6130的脱氨基衍生物,是有效的HCV RNA依赖性RNA聚合酶抑制剂,靶向NS5B聚合酶。 了解更多
  12. Faldaprevir

    Catalog No. A14106
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    HCV Protease 抑制剂
    Faldaprevir是丙型肝炎病毒蛋白酶抑制剂。 了解更多
  13. MK 8742 (elbasvir)

    Catalog No. A13965
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    HCV NS5A 抑制剂
    MK 8742 (elbasvir)是HCV NS5A抑制剂,是一种用于治疗HCV感染的全口服,无干扰素的治疗方案。 了解更多
  14. GS-9451

    Catalog No. A14046
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    HCV NS3/4A protease 抑制剂
    GS-9451是一种新型的丙型肝炎病毒(HCV)非结构性3/4a(NS3/4a)蛋白酶抑制剂,在感染HCV基因型1(GT 1)的患者中具有很高的活性。 了解更多
  15. MK-5172 hydrate

    Catalog No. A15166
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    HCV Protease 抑制剂
    MK-5172 hydrate是目前正在临床开发中的新型P2-P4喹喔啉大环HCV NS3/4a蛋白酶抑制剂。 了解更多
  16. MK-5172 potassium salt

    Catalog No. A15167
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    HCV Protease 抑制剂
    MK-5172 potassium salt是新型P2-P4喹喔啉大环HCV NS3/4a蛋白酶抑制剂。 了解更多
  17. MK-5172 sodium salt

    Catalog No. A15168
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    HCV Protease 抑制剂
    MK-5172 sodium salt是目前正在临床开发中的新型P2-P4喹喔啉大环HCV NS3/4a蛋白酶抑制剂。 了解更多
  18. RO-9187

    Catalog No. A15224
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    HCV replication 抑制剂
    RO-9187是复制系统中HCV病毒复制的有效抑制剂(IC(50)= 171+/-12 nM;CC(50)> 1 mM)。 了解更多
  19. VCH-759

    Catalog No. A15479
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    HCV Polymerase 抑制剂
    VCH-759是HCV RNA依赖性聚合酶的非核苷抑制剂,相对于基因型1a/1b复制子,具有亚微摩尔IC50值。 了解更多
  20. Nesbuvir

    Catalog No. A11510
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    HCV Polymerase 抑制剂
    Nesbuvir是丙型肝炎病毒(HCV) NS5B RNA依赖性RNA聚合酶的选择性抑制剂。 了解更多
  21. Simeprevir

    Catalog No. A11580
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    HCV NS3/4A protease 抑制剂
    Simeprevir是HCV NS3/4A蛋白酶(Ki = 0.36 nM)和病毒复制(replicon EC50 = 7.8 nM)的有效抑制剂。 了解更多
  22. Vaniprevir

    Catalog No. A11600
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    HCV NS3/4A protease 抑制剂
    Vaniprevir是丙型肝炎病毒(HCV)NS3/4A蛋白酶的非共价竞争性抑制剂。 了解更多
  23. Velpatasvir

    Catalog No. A17302
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    HCV NS5A inhibitor
    Velpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. 了解更多
  24. Ombitasvir (ABT-267)

    Catalog No. A17624
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    HCV NS5A inhibitor
    Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a. 了解更多
  25. Paritaprevir (ABT-450)

    Catalog No. A17625
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    HCV NS3/4A inhibitor
    Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. 了解更多
  26. Ledipasvir acetone

    Catalog No. A18055
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    HCV NS5A inhibitor
    Ledipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon. 了解更多
  27. Voxilaprevir

    Catalog No. A12067
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    HCV NS 3/4A protease inhibitor
    Voxilaprevir (GS-9857) is a fluorinated macrocyclic hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor with potent in vitro antiviral activity against genotypes 1-6 HCV and broad coverage of NS3/4A protease polymorphisms. GS-9857 improves coverage against commonly encountered NS3 resistance-associated variants (RAVs). 了解更多
  28. PSI-7409

    Catalog No. A13962
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    nucleotide analog HCV inhibitor
    PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analog inhibitor of HCV. 了解更多
  29. Mericitabine

    Catalog No. A11539
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    HCV NS5B polymerase inhibitor
    Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication. 了解更多
  30. R-1479

    Catalog No. A11540
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    HCV replication inhibitor
    R-1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM). 了解更多
  31. PSI-352938

    Catalog No. A21253
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    HCV nucleotide inhibitor
    PSI-352938 (PSI-938) is a hepatitis C virus (HCV) nucleotide inhibitor. 了解更多
  32. Beclabuvir

    Catalog No. A21511
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    HCV NS5B RNA-dependent RNA polymerase inhibitor
    Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. 了解更多
  33. PSI-7976

    Catalog No. A21631
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    HCV RNA replication inhibitor
    PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. 了解更多
  34. Sofosbuvir impurity C

    Catalog No. A21636
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    HCV RNA replication inhibitor
    Sofosbuvir impurity C is the less active impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. 了解更多
  35. Sofosbuvir impurity A

    Catalog No. A21641
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    HCV RNA replication inhibitor
    Sofosbuvir impurity A, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity. 了解更多
  36. NM107

    Catalog No. A21761
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    HCV NS5B polymerase
    NM107 (2'-C-Methylcytidine) is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, the EC50 of NM107 in the wild-type replicon cells is 1.85 μM. 了解更多
  37. PSI-6206 13CD3

    Catalog No. A21782
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    HCV NS5B polymerase inhibitor
    PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. 了解更多
  38. HCV-IN-3

    Catalog No. A20957
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    HCV NS3/4a protein inhibitor
    HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor, with an IC50 of 20 μM, a Kd of 29 μM. 了解更多
  39. MK-5172

    Catalog No. A13787
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    HCV NS3/4a 抑制剂
    MK-5172是丙型肝炎病毒NS3/4a蛋白酶的选择性抑制剂,在基因型和耐药变异中具有广泛的活性。 了解更多
  40. GS-9256

    Catalog No. A13526
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    HCV NS3 抑制剂
    GS-9451是一种有效的大环HCV NS3 PI,在3天单药治疗后,HCV RNA的中值最大变化达到3.6 log10 IU/mL(范围从-4.7 log10到-3.1 log10 IU/mL)。 I期HCV基因型1感染。 了解更多
  41. BI207127 (Deleobuvir)

    Catalog No. A13414
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    HCV NS5B polymerase 抑制剂
    BI 207127是非核苷类丙型肝炎病毒NS5B聚合酶抑制剂,用于治疗丙型肝炎。 了解更多
  42. Narlaprevir

    Catalog No. A11506
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    NS3 protease 抑制剂
    Narlaprevir是一种有效的、选择性的、口服生物可利用的ns3蛋白酶抑制剂(Ki=6 nM;EC90=40 nM)。 了解更多
  43. Glecaprevir

    Catalog No. A16948
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    HCV NS3/4A protease 抑制剂
    Glecaprevir,也称为ABT-493和A-1282576,是一种新型的HCV NS3/4A蛋白酶抑制剂,IC50值在3.5至11.3 nM之间。 了解更多
  44. Ritonavir

    Catalog No. A10799
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    HIV Protease 抑制剂
    Ritonavir是一种蛋白酶抑制剂,具有抗人类免疫缺陷病毒1型(hiv-1)的活性。蛋白酶抑制剂阻断hiv中被称为蛋白酶的部分,利托那韦抑制hiv病毒蛋白酶,这种蛋白酶防止gag-pol多蛋白的裂解,从而产生非感染性的未成熟病毒颗粒。 了解更多
  45. Lopinavir (ABT-378)

    Catalog No. A10537
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    HIV Protease 抑制剂
    Lopinavir (ABT-378)是HIV蛋白酶的抑制剂。 了解更多
  46. Atazanavir sulfate (BMS-232632-05)

    Catalog No. A10096
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    HIV Protease 抑制剂
    Atazanavir sulfate (BMS-232632-05)是蛋白酶抑制剂(PI)类的抗逆转录病毒药物。是一种高选择性的 HIV-1蛋白酶抑制剂。 了解更多
  47. Atazanavir

    Catalog No. A10097
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    HIV Protease 抑制剂
    Atazanavir是一种氮杂肽及HIV-蛋白酶抑制剂,常与其他抗HIV药物结合,用于治疗HIV感染以及获得性免疫缺乏综合征。 了解更多
  48. Saquinavir

    Catalog No. A11378
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    HIV Protease 抑制剂
    Saquinavir是蛋白酶抑制剂。蛋白酶是将蛋白质分子切割成更小片段的酶。Saquinavir抑制HIV-1和HIV-2蛋白酶。 了解更多
  49. Amprenavir

    Catalog No. A11985
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    Amprenavir是一种人类免疫缺陷病毒(HIV)蛋白酶抑制剂,对于野生型HIV分离株,IC50为14.6±12.5 ng/ml。 了解更多
  50. Indinavir sulfate

    Catalog No. A11871
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    Indinavir sulfate是HIV-1蛋白酶抑制剂。 了解更多

产品 51 到 100 共 245个

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