Angiogenesis

Angiogenesis is the formation and remodelling of new blood vessels and capillaries from growth of pre-existing blood vessels. It normally occurs during wound healing and embryonic development, but is also required for tumour growth and metastasis in cancer.

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  1. NVP-BHG712

    Catalog No. A10661
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    EphB4 抑制剂
    NVP-BHG712是EphB4激酶的选择性抑制剂,在体外对EphB4的选择性超过40多种其他激酶(包括FGFR3)。 了解更多
  2. XL-228

    Catalog No. A13069
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    IGF-1R, Aurora, FGFR, ABL, SRC 抑制剂
    XL228是靶向IGF1R,AURORA激酶,FGFR1-3,ABL和SRC家族激酶的蛋白激酶抑制剂。XL228是一种Aurora A抑制剂(IC50,f3 nmol/L),对ABL1(Ki,5 nmol/L)以及BCR-ABL1 T315I(Ki,1.4 nmol/L)激酶显示出有效的生化活性。 了解更多
  3. KW-2449

    Catalog No. A10508
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    FLT3/FGFR/Bcr-Abl/Aurora 抑制剂
    KW-2449是FLT3、ABl、ABl-T315I和Aurora激酶的多激酶抑制剂。 了解更多
  4. Nintedanib esylate

    Catalog No. A16197
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    RTK 抑制剂
    Nintedanib esylate是多种受体酪氨酸激酶(RTK)和非受体酪氨酸激酶(nRTK)的有效抑制剂。 了解更多
  5. AP24534 (Ponatinib)

    Catalog No. A10080
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    BCR-ABL 抑制剂
    AP24534 (Ponatinib)是有效的多激酶和pan-BCR-ABL抑制剂。 了解更多

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