“angiotensin converting enzyme ace”的搜索结果
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PKC activator
12-O-tetradecanoyl phorbol-13-acetate是佛波醇的二酯,是从巴豆油中提取的促肿瘤化合物。它是在体内和体外以nM浓度可逆的高效蛋白激酶C(PKC)激活剂。
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Ser/Thr protein phosphatase activator
Ceramide是一种神经酰胺,是增殖和分化的有效调节剂,被用作研究与神经酰胺相关的复杂信号传导的工具。
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CPS1 activator
Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
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Nrf2 activator
AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
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p300 HAT activator
CTPB is an activator of p300 HAT (histone acetyltransferase) without PCAF (p300/CBP-associated factor) HAT activities.
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Sirtuin-1 (SIRT1) activator
SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.
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EGFR activator
NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR.
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guanylate cyclase activator
(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator that was in phase I development for the treatment of ischaemic heart disorders. The research has been discontinued.
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dual α/γ PPAR activator
Peliglitazar racemate is the racemate of Peliglitazar. Peliglitazar is a novel dual α/γ PPAR activator.
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histone acetyltransferase activator
YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease.
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SUMO-activating enzyme activator
N106,SUMO活化酶的活化剂,E1连接酶。增加SERCA2a SUMO化和活性,并在体外增强大鼠心肌细胞的收缩性。
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