主页 /
搜索结果：“Tutalthromycin second gen”

“Tutalthromycin second gen”的搜索结果

Quick View
Rigosertib sodium

Catalog No. A21824
Quick View

添加到收藏
multi-kinase inhibitor

Rigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. 了解更多

Bulk Inquiry
Quick View
VP3.15 dihydrobromide

Catalog No. A21789
Quick View

添加到收藏
PDE7/GSK3 inhibitor

VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. 了解更多

Bulk Inquiry
Quick View
IITZ-01

Catalog No. A20192
Quick View

添加到收藏
Lysosomotropic autophagy inhibitor

IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ. 了解更多

Bulk Inquiry
Quick View
KPLH1130

Catalog No. A18494
Quick View

添加到收藏
PDK inhibitor

KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses. KPLH1130 improves glucose tolerance in HFD-fed mice. 了解更多

Bulk Inquiry
Quick View
VP3.15

Catalog No. A18538
Quick View

添加到收藏
dual PDE7/GSK-3 inhibitor

VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). 了解更多

Bulk Inquiry