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Etoricoxib D4
Catalog No. A21877 COX-2 inhibitorEtoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. 了解更多 -
AZD3839 free base
Catalog No. A21606 BACE1 inhibitorAZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor. 了解更多 -
(R)-Rivastigmine D6 tartrate
Catalog No. A21454 cholinesterase inhibitor(R)-Rivastigmine D6 (tartrate) is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor. 了解更多 -
Lanabecestat
Catalog No. A12282 BACE1 inhibitorLanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. 了解更多 -
Naproxen etemesil
Catalog No. A13052 COX-1 and COX-2 inhibitorNaproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. 了解更多 -
Cangrelor Tetrasodium
Catalog No. A17919 P2Y12 receptors inhibitorCangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion. 了解更多 -
Tiagabine hydrochloride
Catalog No. A16135 -
Vigabatrin
Catalog No. A15277 GABA-transaminase 抑制剂Vigabatrin是抑制性神经递质β-氨基丁酸（GABA）的结构类似物，它不可逆地抑制GABA转氨酶对GABA的分解代谢。 了解更多 -
Guvacine hydrochloride
Catalog No. A13613 GABA uptake 抑制剂Guvacine hydrochloride可抑制GABA的摄取（hGABA T-1，rGABA T-2，hGABA T-3和hBGT-1的IC50值分别为14、58、119和1870 uM）。 了解更多 -
SKF 89976A HCl
Catalog No. A10849 GABA uptake 抑制剂SKF 89976A HCl是一种有效的GABA吸收抑制剂，hGAT-1，rGAT-2，hGAT-3和hBGT-1的IC50分别为0.13、550、944和7210μM。 了解更多
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