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  • 搜索结果：“soluble guanylyl cyclase sgc”

“soluble guanylyl cyclase sgc”的搜索结果

18 个项目

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  1. SGC GAK 1
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    SGC GAK 1

    Catalog No. A17120
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    GAK 抑制剂
    SGC GAK 1是一种高亲和力细胞周期蛋白G相关激酶（GAK）抑制剂。 了解更多
  2. SGC 0946
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    SGC 0946

    Catalog No. A12941
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    DOT1L 抑制剂
    SGC 0946是有效的DOT1L甲基转移酶抑制剂，可阻断A431细胞和MCF10A细胞中的H3K79甲基化。 了解更多
  3. SGC-CBP30
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    SGC-CBP30

    Catalog No. A13227
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    CBP/p300 bromodomain 抑制剂
    SGC-CBP30是一种有效且选择性的CREBBP（CBP）和EP300抑制剂，无细胞试验中IC50分别为21 nM和38 nM。它们是一般的转录共激活因子。 了解更多
  4. SGC 707
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    SGC 707

    Catalog No. A15450
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    PRMT3 抑制剂
    SGC 707是PRMT3的有效变构抑制剂（IC50 = 50 nM），其选择性是其他甲基转移酶和其他非表观遗传靶标的100倍以上。 了解更多
  5. NS-2028
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    NS-2028

    Catalog No. A21643
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    sGC inhibitor
    NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity. 了解更多
  6. LRE1
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    LRE1

    Catalog No. A12554
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    soluble adenylyl cyclase inhibitor
    LRE1 is a specific and allosteric inhibitor of soluble adenylyl cyclase. 了解更多
  7. BAY-678
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    BAY-678

    Catalog No. A16866
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    HNE 抑制剂
    BAY-678是人嗜中性粒细胞弹性蛋白酶（HNE）的口服生物利用型，高效，选择性和细胞渗透性抑制剂，IC50为20 nM。BAY-678还被结构基因组学联盟（SGC）提名为化学探针。 了解更多
  8. XY1
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    XY1

    Catalog No. A15807
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    PRMT3 抑制剂
    XY1是SGC 707的负控制。SGC 707（Adooq目录号A15450）是PRMT3的有效，选择性变构抑制剂（IC50 = 50 nM）。 了解更多
  9. SQ22536
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    SQ22536

    Catalog No. A16116
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    adenylyl cyclase 抑制剂
    SQ22536是腺苷酸环化酶的抑制剂，IC50为1.4 uM。它可以抑制完整人血小板中PGE1刺激的cAMP水平升高。 了解更多
  10. NKY 80
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    NKY 80

    Catalog No. A13586
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    Adenylyl Cyclase 抑制剂
    NKY 80是腺苷酸环化酶（AC）的抑制剂。 与AC3和AC2相比，对AC5的亲和力更大（IC50值分别为8.3μM，132μM和1.7 mM）。 了解更多
  11. YHO-13351 free base
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    YHO-13351 free base

    Catalog No. A21568
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    BCRP inhibitor
    YHO-13351 (free base) is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP. 了解更多
  12. DMAPT
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    DMAPT

    Catalog No. A20927
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    NF-κB inhibitor
    DMAPT (Dimethylamino Parthenolide), a water soluble analogue of Parthenolide (PTL), is an oral active NF-κB inhibitor, with a LD50 of 1.7 μM for cell population in AML cells. Has potential anti-cancer and anti-metastatic effect. 了解更多
  13. Retaspimycin
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    Retaspimycin

    Catalog No. A15221
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    Hsp90 inhibitor
    Retaspimycin is a potent and water-soluble inhibitor of Hsp90, with EC50s of 119 nM for both Hsp90 and Grp9. 了解更多
  14. MKC3946
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    MKC3946

    Catalog No. A12508
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    IRE1α inhibitor
    MKC3946 is a potent and soluble IRE1α inhibitor, used for cancer research. 了解更多
  15. AR-9281
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    AR-9281

    Catalog No. A19412
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    s-EH inhibitor
    AR9281 is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH), with potential for the treatment of hypertension and type 2 diabetes. 了解更多
  16. Pelitrexol (AG-2037)
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    • 最新产品

    Pelitrexol (AG-2037)

    Catalog No. A17217
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    GARFT inhibitor
    Pelitrexol is a GARFT inhibitor, and is also a water soluble antifolate with anti-proliferative activity. 了解更多
  17. NB001
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    NB001

    Catalog No. A21185
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    AC1 inhibitor
    NB001 (HTS 09836) is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity. 了解更多
  18. SGC2085
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    SGC2085

    Catalog No. A12272
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    CARM1 inhibitor
    SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 50 nM. 了解更多

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  1. Epigenetics (4)
  2. Cell Metabolism (1)
  3. GPCR / G Protein (2)
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  1. DOT1L (1)
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  3. PRMT3 (2)
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