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搜索结果：“abl”

“abl”的搜索结果

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ON 146040

Catalog No. A16266
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dual PI3K and BCR-ABL 抑制剂

ON 146040是第一个靶向STAT3和STAT5途径的PI3K和BCR-ABL双重抑制剂；抑制PI3Kα/δ同工型，IC50为14/20 nM。了解更多

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GDC-0077

Catalog No. A19494
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PI3Kα inhibitor

GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM). 了解更多

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PI3Kdelta inhibitor 1

Catalog No. A19249
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PI3Kδ inhibitor

PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM. 了解更多

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PP121

Catalog No. A11207
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PI3K 抑制剂

PP121是一种作用于PDGFR，Hck，mTOR，VEGFR2，Src和Abl的多靶点抑制剂，IC50分别为2 nM，8 nM，10 nM，12 nM，14 nM和18 nM，也抑制DNA-PK，IC50为60 nM。了解更多

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