主页 /
搜索结果：“jwh 250”

“jwh 250”的搜索结果

Quick View
GSK2807 Trifluoroacetate

Catalog No. A21731
Quick View

添加到收藏
SMYD3 inhibitor

GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM. 了解更多

Bulk Inquiry
Quick View
A-366

Catalog No. A15969
Quick View

添加到收藏
G9a/GLP 抑制剂

A-366是一种有效的选择性G9a/GLP组蛋白赖氨酸甲基转移酶抑制剂，IC50值为3.3 nM。了解更多

Bulk Inquiry Free Sample
Quick View
GSK343

Catalog No. A13114
Quick View

添加到收藏
EZH2 抑制剂

GSK343是有效的组蛋白H3-赖氨酸27（H3K27）甲基转移酶EZH2抑制剂（IC = 4 nM）。对除EZH1以外的其他HMT的选择性是1000倍（选择性是60倍）。GSK343抑制HCC1806细胞中的H3K27甲基化，IC小于200nM（通过免疫荧光测量）。了解更多

Product Citations (2)

Bulk Inquiry
- Nie L, .et al. CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer, Nat Commun, 2019, Nov 8;10(1):5114 PMID: 31704972
- Yang PM, .et al. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma, Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
Quick View
EPZ-5676 (Pinometostat)

Catalog No. A12735
Quick View

添加到收藏
DOT1L 抑制剂?

EPZ-5676 (Pinometostat)是组蛋白甲基转移酶的小分子抑制剂，具有潜在的抗肿瘤活性。了解更多

Product Citations (2)

Bulk Inquiry Free Sample
- Yoo H, .et al. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function, Cell Death Dis, 2020, Jan; 11(1): 14 PMID: 31908356
- Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48
Quick View
BIX 01294

Catalog No. A11763
Quick View

添加到收藏
G9a/GLP HMT 抑制剂

BIX 01294是一种G9a样蛋白和G9a组蛋白赖氨酸甲基转移酶抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Amodiaquine dihydrochloride dihydrate

Catalog No. A16405
Quick View

添加到收藏
Amodiaquine dihydrochloride dihydrate是人红细胞中组胺N-甲基转移酶的有效，非竞争性抑制剂，也用作抗疟疾和抗炎药。了解更多

Bulk Inquiry