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MRTX1257

Catalog No. A17223
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KRAS-G12C inhibitor

MRTX1257 is a potent, selective, covalent and irreversible inhibitor of KRAS G12C, MRTX1257 inhibited KRAS dependent ERKphosphorylation in the H358cell assay with an IC50= 900 pM. 了解更多

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Antineoplaston A10

Catalog No. A17183
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Ras 抑制剂

Antineoplaston A 10是Ras抑制剂，可能用于治疗神经胶质瘤，淋巴瘤，星形细胞瘤和乳腺癌。了解更多

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BDP9066

Catalog No. A16874
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MRCK 抑制剂

BDP9066是有效的选择性MRCK抑制剂，可减少底物的磷酸化。了解更多

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K-Ras(G12C) inhibitor 9

Catalog No. A14250
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K-Ras(G12C) 抑制剂

K-Ras(G12C) inhibitor 9是致癌性K-Ras（G12C）的变构抑制剂。了解更多

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EHT 1864

Catalog No. A13886
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Rac family GTPase 抑制剂

EHT 1864是一种抑制Rac家族GTPases的抗增殖化学物质。了解更多

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- Kakoki M, .et al. Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production, JCI Insight, 2019, Jun 20;4(12) PMID: 31217360
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EHop-016

Catalog No. A12740
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Rac GTPase Inhibitor

EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration. 了解更多

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NSC 23766

Catalog No. A12546
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Rac1 activation 抑制剂

SC 23766是Rac1-GEF相互作用的选择性抑制剂。通过Rac特异性鸟嘌呤核苷酸交换因子（GEF）TrioN和Tiam1（IC50为50 μM）阻止Rac1激活，而不影响Cdc42或RhoA激活。了解更多

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