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搜索结果：“angiotensin converting enzyme ace”

“angiotensin converting enzyme ace”的搜索结果

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Acetylcysteine

Catalog No. A10032
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Acetylcysteine是一种是ROS抑制剂，拮抗多种蛋白酶体抑制剂的活性。它还是肿瘤坏死因子TNF的抑制剂，主要用作祛痰剂，可处理扑热息痛(对乙酰氨基酚)过量。了解更多

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- Hua Xu, .et al. Preclinical Study Using ABT263 to Increase Enzalutamide Sensitivity to Suppress Prostate Cancer Progression Via Targeting BCL2/ROS/USP26 Axis Through Altering ARv7 Protein Degradation, Cancers (Basel), 2020, Apr; 12(4): 831 PMID: 32235588
- R Kasi, .et al. Melatonin Induces Apoptosis and Inhibits the Proliferation of Cancer Cells via Reactive Oxygen Species-mediated MAPK and mTOR Pathways, Clinical Cancer Drugs, 2020, 2019, 7(1): 44 - 56
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Acemetacin (Emflex)

Catalog No. A11692
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COX 抑制剂

Acemetacin (Emflex)是一种非甾体类抗炎药，是吲哚美辛的乙醇酸酯，是一种环加氧酶抑制剂。了解更多

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Phenacetin

Catalog No. A11906
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Phenacetin是一种非阿片类镇痛药，无抗炎特性。了解更多

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Apocynin (Acetovanillone)

Catalog No. A11989
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NADPH-oxidase 抑制剂

Apocynin (Acetovanillone)是NADPH氧化酶抑制剂。了解更多

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- Liling Su, .et al. Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity, Ecotoxicol Environ Saf, 2022, Jun 1;237:113519 PMID: 35453021
- Shimizu S, .et al. Angiotensin II, a stress-related neuropeptide in the CNS, facilitates micturition reflex in rats, Br J Pharmacol, 2018, Sep;175(18):3727-3737 PMID: 29981238
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Jaceosidin

Catalog No. A12080
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Jaceosidin是一种来源于艾蒿的药理活性黄酮，通过阻断培养的人乳腺上皮细胞中erk-1和-2的磷酸化来抑制佛波酯诱导的cox-2和MMP-9的上调。了解更多

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Acetaminophen

Catalog No. A10030
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COX 抑制剂

Acetaminophen (paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂，IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。它是广泛使用的解热和止痛药。了解更多

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- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
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21-Deacetoxy Deflazacort

Catalog No. A13823
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21-Deacetoxy Deflazacort是Deflazacort（一种系统性的皮质类固醇）的中间体。了解更多

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Gardiquimod TFA

Catalog No. A17050
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TLR7 激动剂

Gardiquimod TFA是一种化合物，可选择性作用于小鼠和人类形式的Toll样受体7（TLR7）。它起免疫反应调节剂的作用。CAS：1020412-43-4（游离碱）了解更多

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Aceclofenac

Catalog No. A17433
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COX-2 抑制剂

Aceclofenac is a cyclooxygenase-2 inhibitor used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. 了解更多

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AKBA

Catalog No. A17908
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Nrf2 activator

AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. 了解更多

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Kynurenic acid

Catalog No. A16581
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GPR35/CXCR8 拮抗剂

Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. 了解更多

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ML604086

Catalog No. A18969
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CCR8 抑制剂

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations. 了解更多

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Aspirin

Catalog No. A11797
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COX-1/COX-2 inhibitor

Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL. 了解更多

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Kynurenic acid sodium

Catalog No. A20000
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GPR35/CXCR8 agonist

Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多

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nor-NOHA acetate

Catalog No. A21673
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Arginase inhibitor

nor-NOHA acetate is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. 了解更多

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(R)-Sulforaphane

Catalog No. A21690
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Keap1/Nrf2/ARE pathway inducer

(R)-Sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. (R)-Sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. 了解更多

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- Isin Cakir, .et al. Sulforaphane reduces obesity by reversing leptin resistance, Elife, 2022, Mar 24 PMID: 35323110
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Aceneuramic acid hydrate

Catalog No. A15585
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Immunomodulator

Aceneuramic acid hydrate是潜在地用于治疗遗传性包涵体肌病（HIBM）的免疫调节剂。了解更多

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