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Etoricoxib D4
Catalog No. A21877 COX-2 inhibitorEtoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. 了解更多 -
PF-4136309
Catalog No. A15127 CCR2 antagonistPF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. 了解更多 -
Kynurenic acid sodium
Catalog No. A20000 GPR35/CXCR8 agonistKynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多 -
GPR35 agonist 1
Catalog No. A12462 GPR35/CXCR8 agonistGPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good druggability. 了解更多 -
Naproxen etemesil
Catalog No. A13052 COX-1 and COX-2 inhibitorNaproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. 了解更多 -
CCR4 antagonist 2
Catalog No. A18471 CCR4 拮抗剂CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. 了解更多 -
Kynurenic acid
Catalog No. A16581 GPR35/CXCR8 拮抗剂Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. 了解更多 -
PF-04634817
Catalog No. A18659 CCR2 /CCR5 dual 拮抗剂PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema. 了解更多 -
MI 2
Catalog No. A12928
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- COX (2)
- CCR (5)
- Toll-like Receptors (1)
- CXCR (3)
- MALT (1)
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- Inhibitor (抑制剂) (4)
- Agonist (激动剂) (3)
- Antagonist (拮抗剂) (5)
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