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  1. LY2365109 hydrochloride

    Catalog No. A21779
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    GlyT1 inhibitor
    LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a. 了解更多
  2. β-Secretase Inhibitor IV

    Catalog No. A21346
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    BACE-1 inhibitor
    β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. 了解更多
  3. Diclofenac

    Catalog No. A17814
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    COX inhibitor
    Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. 了解更多
  4. Naproxen etemesil

    Catalog No. A13052
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    COX-1 and COX-2 inhibitor
    Naproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. 了解更多
  5. Acetyllovastatin

    Catalog No. A19111
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    AChE inhibitor
    Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines. 了解更多
  6. BPN-15606

    Catalog No. A18681
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    γ-secretase modulator
    BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. 了解更多
  7. Deracoxib

    Catalog No. A18077
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    NSAID and COX-2 抑制剂
    Deracoxib is an NSAID and COX-2 inhibitor used to treat osteoarthritis. It induces cell cycle arrest and apoptosis in mammary tumor cells, decreases platelet aggregation, and lowers inflammatory responses. 了解更多
  8. Nerolidol

    Catalog No. A17599
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    AChE inhibitor
    Nerolidol is a synthetic AChE inhibitor and F0F1-ATP synthase modulator. It acts as a sedative, inhibits growth of bacteria and fungi, and decreases the mitochondrial transmembrane electric potential to induce cell death in hepatocarcinoma cells. 了解更多
  9. Naproxen

    Catalog No. A17550
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    COX 抑制剂
    Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. 了解更多
  10. Celecoxib

    Catalog No. A10193
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    COX-2 抑制剂
    Celecoxib是一种磺胺类非甾体抗炎药(NSAID)和选择性COX-2抑制剂,在Sf9细胞中IC50为40 nM。 了解更多

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