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HDAC1/2/3/10 inhibitor
HDAC-IN-7 (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor.
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PDE5/HDAC-1 inhibitor
CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 has potential to treat Alzheimer??s disease.
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HDAC 抑制剂
TC-H 106是一种慢速,紧密结合的I类HDAC(组蛋白脱乙酰基酶)抑制剂。
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HDAC 抑制剂
CI994 (Tacedinaline)是一种组蛋白脱乙酰基酶(HDAC)抑制剂,可在活细胞中诱导组蛋白超乙酰化。
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