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Ripasudil

Catalog No. A15888
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ROCK inhibitor

Ripasudil (K-115) is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension. 了解更多

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Hydroxyfasudil hydrochloride

Catalog No. A15119
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ROCK 抑制剂

Hydroxyfasudil hydrochloride是法舒地尔的代谢产物，是一种有效的Rho激酶抑制剂和血管舒张剂。了解更多

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chroman 1

Catalog No. A15045
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ROCK 抑制剂

Chroman 1 是一种高效且选择性的ROCK II抑制剂。了解更多

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Glycyl-H 1152 2HCl

Catalog No. A13659
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ROCK 抑制剂

Glycyl-H 1152 2HCl是一种选择性有效的ROCK抑制剂（ROCKII，Aurora A，CAMKII，PKG，PKA和PKC的IC50值分别为0.0118、2.35、2.57、3.26，> 10和> 10 uM。）了解更多

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Y-33075 dihydrochloride

Catalog No. A11611
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ROCK inhibitor

Y-33075 dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM. 了解更多

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HA-1077 dihydrochloride

Catalog No. A13785
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ROCK 抑制剂

HA-1077 dihydrochloride通过充当细胞内Ca2+拮抗剂来抑制血管平滑肌收缩。了解更多

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Fasudil HCl (HA-1077)

Catalog No. A10381
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ROCK 抑制剂

Fasudil HCl (HA-1077)是一种环状核苷酸依赖性蛋白激酶抑制剂和Rho相关激酶抑制剂（IC50 = 10.7μM）。了解更多

Product Citations (8)

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- Chengyu Xiang, .et al. Fasudil Ameliorates Osteoporosis Following Myocardial Infarction by Regulating Cardiac Calcitonin Secretion, J Cardiovasc Transl Res, 2022, May 12 PMID: 35551627
- Yeonmi Lee, .et al. Haploidy in somatic cells is induced by mature oocytes in mice, Commun Biol, 2022, Jan 25;5(1):95 PMID: 35079104
- Jiwan Choi, .et al. Efficient hepatic differentiation and regeneration potential under xeno-free conditions using mass-producible amnion-derived mesenchymal stem cells, Stem Cell Res Ther, 2021, Nov 12;12(1):569
- Jee Myung Yang, .et al. Long-term effects of human induced pluripotent stem cell-derived retinal cell transplantation in Pde6b knockout rats, Exp Mol Med, 2021, Apr;53(4):631-642 PMID: 33828232
- Jooyoung Lee, .et al. Hepatogenic Potential and Liver Regeneration Effect of Human Liver-derived Mesenchymal-Like Stem Cells, Cells, 2020, Jun; 9(6): 1521 PMID: 32580448
- Kumar M, .et al. Fasudil hydrochloride ameliorates memory deficits in rat model of streptozotocin-induced Alzheimer's disease: Involvement of PI3-kinase, eNOS and NFκB, Behav Brain Res, 2018, Oct 1;351:4-16 PMID: 29807069
- Wei J, .et al. Inhibition of RHO Kinase by Fasudil Attenuates Ischemic Lung Injury After Cardiac Arrest in Rats, Shock, 2018, Dec;50(6):706-713 PMID: 29283979
- Hofni A, .et al. Fasudil ameliorates endothelial dysfunction in streptozotocin-induced diabetic rats: a possible role of Rho kinase, Naunyn Schmiedebergs Arch Pharmacol, 2017, Aug;390(8):801-811 PMID: 28493050