“Ligand-gated Ion Channels”的搜索结果

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  1. Ulipristal acetate

    Catalog No. A21041
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    progesterone receptor modulator
    Ulipristal (acetate) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma. 了解更多
  2. (R)-Elagolix

    Catalog No. A21184
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    GnRHR antagonist
    Elagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM). 了解更多
  3. Lisinopril

    Catalog No. A21064
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    angiotensin-converting enzyme inhibitor
    Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. 了解更多
  4. Azilsartan medoxomil monopotassium

    Catalog No. A20860
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    angiotensin II receptor type 1 antagonist
    Azilsartan medoxomil monopotassium is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. 了解更多
  5. Beclometasone dipropionate

    Catalog No. A17254
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    glucocorticoid agonist
    Beclometasone dipropionate is a potent glucocorticoid agonist; it is a prodrug of the free form, beclometasone. 了解更多
  6. Tamoxifen

    Catalog No. A16738
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    selective estrogen receptor modulator (SERM)
    Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. 了解更多
  7. ROR agonist-1

    Catalog No. A18569
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    ROR 激动剂
    ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5. 了解更多
  8. S18-000003

    Catalog No. A19105
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    RORγt 抑制剂
    S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production. 了解更多
  9. Lasofoxifene Tartrate

    Catalog No. A18097
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    selective Estrogen receptor modulator
    Lasofoxifene tartrate is a third-generation selective estrogen receptor modulator. 了解更多
  10. Fluorometholone

    Catalog No. A17651
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    glucocorticoid
    Fluorometholone is a glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. 了解更多
  11. Fimasartan

    Catalog No. A17477
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    non-peptide angiotensin II receptor antagonist
    Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys. 了解更多
  12. Fluticasone propionate

    Catalog No. A11860
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    Fluticasone propionate是一种高亲和力的选择性糖皮质激素受体激动剂(Kd = 0.5 nM)。 了解更多
  13. 17 alpha-propionate

    Catalog No. A10009
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    Androgen 拮抗剂
    17 alpha-propionate是一种新型的局部和外周选择性雄激素拮抗剂。 了解更多
  14. Betamethasone dipropionate

    Catalog No. A10130
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    Glucocorticoid Receptor 激动剂
    Betamethasone Dipropionate是糖皮质激素类固醇,具有抗炎和免疫抑制特性。 了解更多
  15. Dienogest

    Catalog No. A10308
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    Dienogest是一种口服抗孕激素,具有抗雄激素活性,因此可以改善雄激素症状。 了解更多

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