“betaine hydrochloride”的搜索结果
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p38 MAPK inhibitor
SB 203580 hydrochloride (RWJ 64809 hydrochloride) is a widely used p38 MAPK inhibitor.
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p38α MAPK inhibitor
MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.
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p38α MAPK inhibitor
BMS-582949 hydrochloride is an orally active and highly selective p38α MAPK inhibitor, with an IC50 of 13 nM.
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VEGFR1/2/3/PDGFRβ/Kit/RET/Raf-1 inhibitor
Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
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Raf 抑制剂
CEP-32496 hydrochloride是野生型BRAF,V600E突变型BRAF和c-Raf的高效抑制剂,Kd值分别为14 nM,36 nM和39 nM。
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JNK 抑制剂
CC-401 hydrochloride是具有潜在抗肿瘤活性的第二代ATP竞争性蒽并吡喃酮c-Jun N末端激酶(JNK)抑制剂。
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p38α MAPK inhibitor
MW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.
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Raf kinase inhibitor
B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively.
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p38 MAPK 抑制剂
DBM 1285 dihydrochloride是p38 MAPK抑制剂。在巨噬细胞和体内抑制p38磷酸化和LPS诱导的TNF-α产生。
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Raf 抑制剂
ML 786 dihydrochloride是一种有效的Raf激酶抑制剂(B-RafV600E,C-Raf和野生型B-Raf的IC50值分别为2.1、2.5和4.2 nM)。
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p38 MAPK 抑制剂
SKF 86002 Dihydrochloride是p38 MAP激酶的抑制剂(IC50 = 0.1-1 uM)。有效抑制人单核细胞中LPS诱导的IL-1和TNF-α的产生(IC50 = 1 uM)。
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