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Ryanodine

Catalog No. A12898
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Ryanodine receptor modulator

Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. 了解更多

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PD-1-IN-1

Catalog No. A12184
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immune modulator

PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO2015033299A1, compound example 4. PD-1-IN-1 can be used as immune modulator. 了解更多

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KL1333

Catalog No. A17234
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NAD+ Modulator

KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL-1333 Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. 了解更多

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BPN-15606

Catalog No. A18681
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γ-secretase modulator

BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. 了解更多

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Caldaret

Catalog No. A13148
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intracellular Ca2+ handling modulator

Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition. 了解更多

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Tamoxifen

Catalog No. A16738
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selective estrogen receptor modulator (SERM)

Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. 了解更多

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3-Methoxytyramine

Catalog No. A21676
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neuromodulator

3-Methoxytyramine, a well known extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator. 了解更多

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Biricodar

Catalog No. A21464
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P-glycoprotein/MRP-1 modulator

Biricodar (VX-710) is a modulator of P-glycoprotein and MRP-1; shows effective chemosensitizing activity in multidrug resistant cells. 了解更多

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