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SMYD2-IN-1
Catalog No. A19908 SMYD2 inhibitorSMYD2-IN-1 is a SMYD2 inhibitor extracted from patent WO2016166186A1, compound example 1.1, has an IC50 of 4.45 nM. 了解更多 -
PROTAC BET Degrader-1
Catalog No. A20016 BET degraderPROTAC BET Degrader-1 is a potent BET degrader based on PROTAC, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration. 了解更多 -
Thalidomide-O-amido-PEG3-C2-NH2
Catalog No. A20161 E3 ligase ligand-linker conjugateThalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. 了解更多 -
BET-IN-2
Catalog No. A20162 -
Heterocyclyl carbamate derivative 1
Catalog No. A20163 Heterocyclyl carbamate derivative 1 is a heterocyclyl carbamate derivative that may be used for the research of inflammatory and neurological diseases. 了解更多 -
FK1052 hydrochloride
Catalog No. A20164 5-HT3 /5-HT4 receptor dual antagonistFK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist. 了解更多 -
EOAI3402143
Catalog No. A20166 DUB inhibitorEOAI3402143 is a deubiquitinase (DUB) inhibitor, which inhibits dose-dependently inhibits Usp9x/Usp24 and Usp5. 了解更多 -
Polymyxin B nonapeptide
Catalog No. A20168 Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes. 了解更多 -
(S,R,S)-AHPC-PEG6-C4-Cl
Catalog No. A20169 (S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. 了解更多 -
DC1SMe
Catalog No. A20181 DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. 了解更多 -
AM-92016 hydrochloride
Catalog No. A20472 IK blockerAM-92016 hydrochloride is a specific blocker of rectifier potassium current (IK). 了解更多 -
PAβN dihydrochloride
Catalog No. A22016 efflux pump inhibitorPAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor. 了解更多 -
Oct3/4-inducer-1
Catalog No. A22642 Oct3/4 inducerOct3/4-inducer-1 (compound 2) is a potent Oct3/4 inducer. Oct3/4-inducer-1 promotes expression and stabilization of Oct3/4, and enhances its transcriptional activity in diverse human somatic cells. 了解更多 -
Motixafortide
Catalog No. A22276 CXCR4 antagonistMotixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ??1 nM. 了解更多 -
MRK-016
Catalog No. A12046 GABAA α5 receptor agonistMRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77?and 1.4?nM for human?GABAA?α1β3γ2, GABAA?α2β3γ2, GABAA?α3β3γ2, and GABAA?α5β3γ2, respectively; MRK-016 also readily penetrates the CNS. 了解更多
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