“Ant”的搜索结果

产品 51 到 100 共 8696个

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  1. BD750

    Catalog No. A22300
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    JAK3/STAT5 inhibitor
    BD750, an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation, with IC50 values of 1.5 μM and 1.1 μM in mouse and human T cells, respectively. 了解更多
  2. Gallein

    Catalog No. A22304
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    Gβγ subunit signalling inhibitor
    Gallein is a G protein βγ (Gβγ) subunit signalling inhibitor. Gallein disrupts the interaction of Gβγ subunits with the PI3Kγ. Anticancer agent. 了解更多
  3. BDTX-189

    Catalog No. A22306
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    Anticancer agent
    BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity. 了解更多
  4. 2-Phospho-L-ascorbic acid trisodium

    Catalog No. A22309
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    antioxidant
    2-Phospho-L-ascorbic acid trisodium acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. 了解更多
  5. L-Quebrachitol

    Catalog No. A22312
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    natural product
    L-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway. 了解更多
  6. Loureirin A

    Catalog No. A22313
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    flavonoid
    Loureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity. 了解更多
  7. ABTL-0812

    Catalog No. A22321
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    antineoplastic agent
    ABTL-0812 (α-Hydroxylinoleic acid) induces endoplasmic reticulum (ER) stress-mediated autophagy. ABTL-0812 is a first-in-class small molecule with anti-cancer activity. 了解更多
  8. Mobocertinib

    Catalog No. A22334
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    inhibitor of EGFR and HER2 oncogenic mutants
    Mobocertinib (TAK-788) is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity. 了解更多
  9. ASP4132

    Catalog No. A22339
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    AMPK activator
    ASP4132 is an orally active, potent AMPK activator with an EC50 of 18 nM. ASP4132 has anti-cancer activity and makes tumor regression in breast cancer xenograft mouse models. 了解更多
  10. Decursinol angelate

    Catalog No. A22340
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    cytotoxic and protein kinase C (PKC) activating agent
    Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities. 了解更多
  11. Dihydrocaffeic acid

    Catalog No. A22344
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    Antioxidant agent
    Dihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity. 了解更多
  12. AUDA

    Catalog No. A22346
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    sEH inhibitor
    AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively. AUDA has anti-inflammatory activity. 了解更多
  13. 3-Deazaadenosine hydrochloride

    Catalog No. A22347
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    inhibitor of S-adenosylhomocysteine hydrolase
    3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 ?M; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity. 了解更多
  14. 7,4'-Di-O-methylapigenin

    Catalog No. A22349
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    antifungal
    The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines. 了解更多
  15. Pyridoxine

    Catalog No. A22350
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    antioxidant agent
    Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. 了解更多
  16. Nootkatone

    Catalog No. A22352
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    neuroprotective agent
    Nootkatone, a neuroprotective agent from Alpiniae Oxyphyllae Fructus, has antioxidant and anti-inflammatory effects. 了解更多
  17. Beta-asarone

    Catalog No. A22354
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    neuroprotection agent
    Beta-Asarone, found in certain plants such as Acorus and Asarum, could pass the blood-brain barrier and exerts neuroprotection effects. 了解更多
  18. Coumarin-3-carboxylic Acid

    Catalog No. A22355
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    antiproliferative agent
    Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line. 了解更多
  19. (2S,3R,4S)-4-Hydroxyisoleucine

    Catalog No. A22356
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    anti-diabetes agent
    (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound isolated from Trigonella foenum-graecum, with anti-diabetes and anti-diabetic nephropathy activity. 了解更多
  20. Solamargine

    Catalog No. A22357
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    anticancer agent
    Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. 了解更多
  21. 5-Bromoindole

    Catalog No. A22363
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    inhibitor of glycogen synthase kinase 3
    5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3). 了解更多
  22. Avacopan

    Catalog No. A22202
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    selective C5aR antagonist
    Avacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist. 了解更多
  23. Ozogamicin

    Catalog No. A12672
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    antibody-drug conjugate Linker
    Ozogamicin is an antibody-drug conjugate Linker. 了解更多
  24. Emedastine

    Catalog No. A22158
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    histamine H1 receptor antagonist
    Emedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. 了解更多
  25. CB-103

    Catalog No. A22160
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    protein-protein interaction (PPI) inhibitor
    CB-103 is a first-in-class, orally active protein-protein interaction (PPI) inhibitor of the NOTCH transcriptional activation complex. CB-103 has anti-tumor activity. 了解更多
  26. Cenobamate

    Catalog No. A22163
    antiepileptic drug
    Cenobamate (YKP-3089) is a novel antiepileptic drug candidate with broad-spectrum anticonvulsant activity. 了解更多
  27. Molnupiravir

    Catalog No. A22165
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    broad-spectrum antiviral activity
    Molnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19. 了解更多
  28. Laninamivir octanoate

    Catalog No. A22166
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    neuraminidase (NA) inhibitor
    Laninamivir octanoate (CS-8958), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. 了解更多
  29. Lycorine

    Catalog No. A22170
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    SCAP inhibitor
    Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. 了解更多
  30. Gentiopicroside

    Catalog No. A22172
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    antianti-inflammatoryand antioxidative effects
    Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 ?M and 22.8 ?M for CYP2A6; Gentiopicroside has antianti-inflammatoryand antioxidative effects. 了解更多
  31. Eleutheroside B1

    Catalog No. A22173
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    anti-human influenza virus efficacy
    Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 ?g/ml. Antiviral and anti-inflammatory activities. 了解更多
  32. Periplogenin

    Catalog No. A22174
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    anti-psoriatic agent
    Periplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation. 了解更多
  33. Oxyberberin

    Catalog No. A22175
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    natural alkaloid
    Berlambine is a natural alkaloid isolated from many plants. 了解更多
  34. Groenlandicine

    Catalog No. A22176
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    protoberberine alkaloid
    Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). 了解更多
  35. 6-Methoxydihydroavicine

    Catalog No. A22177
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    antiplatelet activities
    6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro. 了解更多
  36. ALK2-IN-1

    Catalog No. A22183
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    inhibitor of Activin receptor-like kinase (ALK2) mutant R206H
    ALK2-IN-1 (BLU-782) is a potent and selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of <10 nM. 了解更多
  37. BIO-013077-01

    Catalog No. A22185
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    antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4
    BIO-013077-01, Novel potent antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4. 了解更多
  38. Practolol

    Catalog No. A22186
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    β1-adrenergic receptor antagonist
    Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias. 了解更多
  39. GR 125743

    Catalog No. A22189
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    5-HT1B/1D receptor antagonis
    GR 125743 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively. 了解更多
  40. Retigabine

    Catalog No. A22223
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    anticonvulsant
    Retigabine (D-23129) is a novel anticonvulsant with activity in a broad range of seizure models. 了解更多
  41. Orelabrutinib

    Catalog No. A22225
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    Bruton's tyrosine kinase (BTK) inhibitor
    Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. 了解更多
  42. Dextromethorphan

    Catalog No. A22212
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    antitussive drug
    Dextromethorphan (Discontinued) (DXM or DM) is an antitussive (cough suppressant) drug of the morphinan class with sedative and dissociative properties. 了解更多
  43. KN-93 phosphate

    Catalog No. A22229
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    membrane-permeant synthetic inhibitor
    KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. 了解更多
  44. DS-1001b

    Catalog No. A22236
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    mutant IDH-1 inhibitor
    DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity. 了解更多
  45. VTP50469

    Catalog No. A22238
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    Menin-MLL interaction inhibitor
    VTP50469 is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a Ki of 104 pM. VTP50469 has potently anti-leukemia activity. 了解更多
  46. Mobocertinib succinate

    Catalog No. A22240
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    EGFR/HER2 oncogenic mutants inhibitor
    Mobocertinib succinate (TAK-788 succinate) is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity. 了解更多
  47. HS-1793

    Catalog No. A22248
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    Anti-tumor inhibitor
    HS-1793 is a resveratrol analogue. HS-1793 downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model. 了解更多
  48. TSPC (HUN86320)

    Catalog No. A22250
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    inhibitor for GA perception
    TSPC is an inhibitor for GA perception by in vitro and in planta evaluations. 了解更多
  49. Imidacloprid-urea

    Catalog No. A22253
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    marine xenobiotic metabolite
    Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid. 了解更多
  50. AQX-016A

    Catalog No. A22254
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    activator of SHIP-1
    AQX-016A is a potent activator of SHIP-1 that induces apoptosis of the cancer cell lines in vitro in both a time and dose dependant manner. 了解更多

产品 51 到 100 共 8696个

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