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Uridine triphosphate
Catalog No. A13317 nucleotideUridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states. 了解更多 -
PF-05241328
Catalog No. A20052 Nav1.7 inhibitorPF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM. 了解更多 -
Trimebutine maleate
Catalog No. A18115 ?- opioid receptor agonistTrimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. 了解更多 -
Tetracaine
Catalog No. A18099 Tetracaine is a potent local anesthetic. It alters the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. 了解更多 -
Fluralaner
Catalog No. A18068 Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels. 了解更多 -
Nefazodone hydrochloride
Catalog No. A17622 5-HT2 receptors inhibitorNefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多 -
Efonidipine
Catalog No. A17478 Calcium channel blockerEfonidipine is a dihydropyridine calcium channel blocker that blocks both T-type and L-type calcium channels. It has also been studied in atherosclerosis and acute renal failure. 了解更多 -
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最新产品
SAR-7334 HCl
Catalog No. A17237 TRPC6 inhibitorSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected. 了解更多 -
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ICA-121431
Catalog No. A13773 NaV1.3 and NaV1.1 channels 抑制剂ICA-121431是人NaV1.3和NaV1.1通道的有效和选择性抑制剂（IC50值分别为13和23 nM）。 了解更多 -
GW 542573X
Catalog No. A13944 -
Proparacaine HCl
Catalog No. A11715 Voltage-gated sodium channels 拮抗剂Proparacaine HCl是一种电压门控钠通道拮抗剂，ED50为3.4 mM。 了解更多 -
Guanosine 5'-triphosphate trisodium salt
Catalog No. A18283 Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) is an activator of signal transduction of G proteins. 了解更多 -
Triphala
Catalog No. A16067 Anti-adipogenic, anti-inflammatory, and anti-neoplastic activitiesTriphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica. Triphala inhibits NF-κB activation. Triphala exerts antifungal action. Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities. 了解更多 -
Adenosine deaminase
Catalog No. A19330 Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. 了解更多 -
Cinnamylamine
Catalog No. A20835 Cinnamylamine can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. 了解更多 -
Peptide 401
Catalog No. A13913 Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT). 了解更多 -
TLR4-IN-C34
Catalog No. A22057 TLR4 inhibitorTLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. 了解更多 -
Filastatin
Catalog No. A22063 Candida albicans filamentation inhibitorFilastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. 了解更多 -
WAY-169916
Catalog No. A22105 pathway-selective inhibitor of estrogen receptor (ER)WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER) that acts by inhibiting NF-kB transcriptional activity. 了解更多 -
GSK106 hydrochloride
Catalog No. A22116 negative control compoundGSK106 is a negative control compound that can be used in binding and functional assays for PAD4 inhibitors. 了解更多 -
FLTX1
Catalog No. A22120 antiestrogenic propertiesFLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus. 了解更多 -
Epiblastin A
Catalog No. A22121 inhibitor of Casein Kinase 1 (CK1)Epiblastin A is an inhibitor of Casein Kinase 1 (CK1) that engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). 了解更多 -
Takeda103A
Catalog No. A22142 bovine tubulin oxidation inhibitorTakeda103A is a potent GRK2-dependent bovine tubulin oxidation inhibitor. 了解更多 -
Soporidine
Catalog No. A22145 strigolactone (SL) antagonistSoporidine is a strigolactone (SL) antagonist and inhibitor of germination in their biological assays. It binds AtHTL and specifically interferes with SL signaling. 了解更多 -
ERDRP-0519
Catalog No. A22150 inhibitor of polymeraseERDRP-0519 is an orally available inhibitor of polymerase that shows efficacy against a lethal morbillivirus infection in a large animal model. 了解更多 -
Aka Lumine
Catalog No. A22152 luciferin analogueAka Lumine, a luciferin analogue, is a luciferase substrate emitting red, green, and blue light. The longest emission wavelength of Aka Lumine is recorded at 675 nm, which is within the NIR region. 了解更多 -
Remimazolam besylate
Catalog No. A22198 ultra short-acting benzodiazepineRemimazolam besylate is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. 了解更多 -
RGD peptide (GRGDNP)
Catalog No. A22271 integrin-ligand interactions inhibitorRGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation. 了解更多 -
L-2-Hydroxyglutaric acid disodium
Catalog No. A22281 epigenetic modifierL-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. 了解更多
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