“betaine hydrochloride”的搜索结果
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Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.
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Tinoridine hydrochloride is a nonsteroidal anti-inflammatory drug and also has potent radical scavenger and antiperoxidative activity.
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Adrenergic alpha-1 agonist
Midodrine hydrochloride is an ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of hypotension. It improves clinical outcome of chronic hypotension.
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antibiotic
Pivmecillinam hydrochloride is active against gram-negative organisms and used as for amdinocillin. Pivmecillinam is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic.
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Acid pump antagonist
Revaprazan hydrochloride is a novel acid pump antagonist (APA). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection.
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MAO inhibitor
Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension.
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oxidative phosphorylation blocker
Imeglimin hydrochloride是新型含四氢三嗪的口服降糖药中的第一个,即glimins。已证明它可作用于肝脏,肌肉和胰腺γ-细胞,以独特地靶向2型糖尿病的关键缺陷。
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MET/Axl 抑制剂
Glesatinib hydrochloride是MET和Axl受体酪氨酸激酶途径的抑制剂,当改变时,它们会驱动肿瘤的生长。
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Topoisomerase 抑制剂
Voreloxin hydrochloride是一种小分子,是具有抗肿瘤活性的萘啶类似物;Topo II抑制剂。
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VEGFR 抑制剂
Vandetanib hydrochloride是一种有效的VEGFR2抑制剂,IC50为40 nM。
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NK3 receptor 拮抗剂
Talnetant Hydrochloride是一种有效且选择性的NK3受体拮抗剂(ki = 1.4 nM,hNK-3-CHO);对hNK-3受体的选择性是对hNK-2受体的100倍,在浓度高达100 uM时对hNK-1没有亲和力。
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PI3K 抑制剂?
NVP-BKM120 Hydrochloride是p110α/β/δ/γ的选择性PI3K抑制剂,IC50分别为52 nM/166 nM/116 nM/262 nM。对VPS34,mTOR,DNA-PK的效力降低,对PI4Kβ几乎没有活性。
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ROCK 抑制剂
Hydroxyfasudil hydrochloride是法舒地尔的代谢产物,是一种有效的Rho激酶抑制剂和血管舒张剂。
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EGFR 抑制剂
Gefitinib hydrochloride是一种EGFR抑制剂,可通过靶细胞中的表皮生长因子受体(EGFR)中断信号传导。因此,它仅在EGFR突变和过度活跃的癌症中有效。
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Pim 抑制剂
CX-6258 hydrochloride hydrate是一种有效的,口服有效的Pim 1/2/3激酶(IC50 = 5 nM/25 nM/16 nM)抑制剂,具有出色的生化效能和激酶选择性。
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D3/D2 Dopamine Receptor 拮抗剂
Cariprazine hydrochloride是一种新型的抗精神病药物,对多巴胺D3(Ki = 0.09 nM)和D2(Ki = 0.5 nM)受体具有高选择性和亲和力,对5-羟色胺5-HT(1A)受体具有中等亲和力。
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Terbinafine hydrochloride (Lamisil)是烯丙胺类抗真菌药的一种,是通过角鲨烯环氧酶抑制作用合成麦角固醇的特异性抑制剂。
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Dapoxetine hydrochloride是通过抑制5-羟色胺转运蛋白,增加5-羟色胺在突触后裂隙中的作用并因此促进射精延迟而起作用。
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CRAC channel inhibitor
RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM.
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partial agonist of Trace amine-associated receptor 1
RO5203648 hydrochloride is a partial agonist of Trace amine-associated receptor 1 (TAAR1).
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inhibitor of coactivator associated arginine methyltransferase 1 (CARM1)
SGC2085 hydrochloride is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with IC50 of 50 nM.
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ATP-competitive CDK2 and CDK5 inhibitor
PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor.
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inhibitor of S-adenosylhomocysteine hydrolase
3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 ?M; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.
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MELK inhibitor
OTSSP167 (hydrochloride) is a highly potent MELK inhibitor with IC50 value of 0.41 nM.
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GABAB receptor positive allosteric modulator
SSD114 hydrochloride is a novel GABAB receptor positive allosteric modulator.
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sodium channel blocker
Levobupivacaine hydrochloride is a sodium channel blocker.
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muscarinic acetylcholine receptor antagonist
Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist.
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inhibitor of KCNJ1
KCNJ1 (Kir1.1, or renal outer medullary potassium channel) and KCNJ13 (Kir7.1) are inwardly rectifying two-transmembrane K+ channels. KCNJ1 has critical roles in kidney function, while KCNJ13 is important in the eye, kidney, and small intestine. VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM) which also causes 70% inhibition of KCNJ13 at 10 ?M. It has no effect on the related channels KCNJ2 (Kir2.1) and KCNJ10 (Kir4.1) at a concentration of 10 ?M.
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norepinephrine reuptake inhibitor
(R)-Viloxazine Hydrochloride is the R-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant.
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norepinephrine reuptake inhibitor
(S)-Viloxazine Hydrochloride is the S-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant.
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antioxidant agent
Diphenylamine hydrochloride, an organic compound isolated from coriander, is used mainly for its antioxidant properties. Diphenylamine is used as an industrial antioxidant, dye mordant and is also applied in agriculture as a fungicide and antihelmintic.
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VEGFR-2/FGFR inhibitor
CP-547632 hydrochloride is a well-tolerated, orally-bioavailable inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases with IC50s of 11 nM and 9 nM, respectively.
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NQO2 inhibitor
Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor.
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5-HT3 partial agonist
Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
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(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
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GABA receptor agonist
Isoguvacine hydrochloride is a GABA receptor agonist.
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OABK hydrochloride is a small-molecule switch that can be used to control protein activity.
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δ opioid receptor antagonist
Naltrindole hydrochloride is a highly potent and selective non-peptide δ opioid receptor antagonist with a Ki of 0.02 nM.
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IK blocker
AM-92016 hydrochloride is a specific blocker of rectifier potassium current (IK).
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ROMK inhibitor
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM.
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calcium channel blocker
Tiapamil hydrochloride is a calcium channel blocker.
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CB1 agonist
Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status.
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neuropeptide Y5 receptor antagonist
CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
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oxytocin receptor antagonist
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively, used as a tocolytic agent.
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AdipoR agonist
AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively.
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5-HT2C receptor-selective agonist
Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.
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dopamine transporter/norepinephrine transportertransporters inhibitor
Radafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator.
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dopamine D2/D3 receptor antagonist
Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.
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L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of homocysteine; prevents translational incorporation of homocysteine into proteins.
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5-HT1B receptor antagonist
SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.
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