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L-Quebrachitol
Catalog No. A22312 natural productL-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway. 了解更多 -
Loureirin A
Catalog No. A22313 flavonoidLoureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity. 了解更多 -
Higenamine
Catalog No. A22315 β2-AR agonistHigenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. 了解更多 -
Remibrutinib
Catalog No. A22322 BTK inhibitorRemibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. 了解更多 -
Benzamidine hydrochloride
Catalog No. A22323 trypsin-like serine proteases inhibitorBenzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 ?M, 21 ?M, 20 ?M and 110 ?M for uPA, trypsin, tryptase and factor Xa, respectively. 了解更多 -
IRAK4-IN-4
Catalog No. A22333 IRAK4 inhibitorIRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. 了解更多 -
3'-Hydroxypterostilbene
Catalog No. A22341 natural pterostilbene analogue3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 ?M for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 了解更多 -
Dihydrocaffeic acid
Catalog No. A22344 Antioxidant agentDihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity. 了解更多 -
JNJ-38158471
Catalog No. A22345 VEGFR-2 inhibitorJNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively. 了解更多 -
CCG-222740
Catalog No. A22348 MRTF pathway inhibitorCCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor. CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. 了解更多 -
7,4'-Di-O-methylapigenin
Catalog No. A22349 antifungalThe compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines. 了解更多 -
Timosaponin AIII
Catalog No. A22353 Inhibitor of U46619-induced Rat Platelet AggregationTimosaponin AIII is a potent Inhibitor of U46619-induced Rat Platelet Aggregation, Selectively Inhibiting TxA2-induced Platelet Activation, Preferably Suppressing TP-mediated Activation of Gq, not G12/13, Signaling Pathways. 了解更多 -
Coumarin-3-carboxylic Acid
Catalog No. A22355 antiproliferative agentCoumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line. 了解更多 -
Remimazolam
Catalog No. A22200 benzodiazepine derivative drugRemimazolam, also known as CNS-7056, is a benzodiazepine derivative drug, developed by PAION, in collaboration with Japanese licensee Ono Pharmaceutical as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures. 了解更多 -
Dehydroascorbic acid
Catalog No. A12366 potent cerebroprotectionDehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. 了解更多 -
Emedastine
Catalog No. A22158 histamine H1 receptor antagonistEmedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. 了解更多 -
Conoidin A
Catalog No. A22167 cell permeable inhibitorConoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII). 了解更多 -
Eurycomanone
Catalog No. A22171 Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. 了解更多 -
Periplogenin
Catalog No. A22174 anti-psoriatic agentPeriplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation. 了解更多 -
Groenlandicine
Catalog No. A22176 protoberberine alkaloidGroenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). 了解更多 -
6-Methoxydihydroavicine
Catalog No. A22177 antiplatelet activities6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro. 了解更多 -
NSC23005 free acid
Catalog No. A22180 p18INK inhibitorNSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM). 了解更多 -
BIO-013077-01
Catalog No. A22185 antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4BIO-013077-01, Novel potent antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4. 了解更多 -
Thiambutosine
Catalog No. A22187 candidate for treatment of lepromatous leprosyThiambutosine was a candidate for treatment of lepromatous leprosy. 了解更多 -
SSD114 hydrochloride
Catalog No. A22188 GABAB receptor positive allosteric modulatorSSD114 hydrochloride is a novel GABAB receptor positive allosteric modulator. 了解更多 -
Isocyclosporin A
Catalog No. A22205 Isocyclosporin A is a rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions. 了解更多 -
Cholesterol
Catalog No. A22211 endogenous estrogen-related receptor α (ERRα) agonistCholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist. 了解更多
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