“17”的搜索结果

产品 201 到 250 共 2939个

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  1. Nitromifene

    Catalog No. A20417
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    ER antagonist
    Nitromifene is an antagonist of estrogen receptor (ER). 了解更多
  2. Xenalamine

    Catalog No. A20411
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    Xenalamine is a synthetic antiviral agent. 了解更多
  3. Simurosertib

    Catalog No. A20392
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    CDC7 inhibitor
    Simurosertib (TAK-931) is a selective cycle 7 (CDC7) kinase inhibitor, with an IC50<0.3 nM. 了解更多
  4. B220

    Catalog No. A20391
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    B220 is an antiviral agent which can inhibit the growth of HSV-1, HSV-2 and human cytomegalovirus (CMV). 了解更多
  5. PD 117519

    Catalog No. A20388
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    A2A adenosine agonist
    PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models. 了解更多
  6. (±)-Zanubrutinib

    Catalog No. A20381
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    Btk inhibitor
    (±)-Zanubrutinib is a potent, selective and orally available Bruton's tyrosine kinase (Btk) inhibitor. 了解更多
  7. BTTAA

    Catalog No. A20374
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    BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF. 了解更多
  8. RMI 10874

    Catalog No. A20370
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    RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone. 了解更多
  9. CDD3505

    Catalog No. A20364
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    CDD3505 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity. 了解更多
  10. Fisogatinib

    Catalog No. A20354
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    FGFR4 inhibitor
    Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM. 了解更多
  11. RD3-0028

    Catalog No. A20348
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    RSV replication inhibitor
    RD3-0028 is a potent and selective inhibitor of RSV replication with an EC50 of 4.5 μM. 了解更多
  12. Folcisteine

    Catalog No. A20317
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    plant growth regulator
    Folcisteine is a plant growth regulator. 了解更多
  13. PDD 00017273

    Catalog No. A20305
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    PARG inhibitor
    PDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with an IC50 of 26 nM, and a KD of 1.45 nM. 了解更多
  14. TL02-59

    Catalog No. A20302
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    Src-family kinase Fgr inhibitor
    TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM. 了解更多
  15. ML230

    Catalog No. A20298
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    ABCG2 inhibitor
    ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively. 了解更多
  16. Abaperidone

    Catalog No. A20286
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    5-HT2A/dopamine D2 antagonist
    Abaperidone is a potent antagonist of 5-HT2A?receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM. 了解更多
  17. Linperlisib

    Catalog No. A20275
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    PI3Kδ inhibitor
    Linperlisib is a potent and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM. 了解更多
  18. Tyk2-IN-5

    Catalog No. A20268
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    Tyk2 inhibitor
    Tyk2-IN-5 (compound 6) is a highly potent, selective and orally active Tyk2 inhibitor and targets the JH2 domain, with a Ki of 0.086 nM for Tyk2 JH2 and an IC50 of 25 nM for IFNα. 了解更多
  19. Oxamflatin

    Catalog No. A20265
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    HDAC inhibitor
    Oxamflatin (Metacept-3) is a potent HDAC inhibitor with an IC50 of 15.7 nM. 了解更多
  20. α-2,3-sialyltransferase-IN-1

    Catalog No. A20249
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    α-2,3-sialyltransferase inhibitor
    α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM. 了解更多
  21. YM17E

    Catalog No. A20229
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    acyl CoA inhibitor
    YM17E is an inhibitor of acyl CoA:cholesterol acyltransferase (ACAT), with IC50 of 44 nM in rabbit liver microsomes in vitro. 了解更多
  22. Palmitodiolein

    Catalog No. A20217
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    Palmitodiolein (Triglyceride POO) is a triacylglycerol which is present in vegetable oils. 了解更多
  23. (S,R,S)-AHPC-PEG4-N3

    Catalog No. A20214
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    E3 ligase ligand-linker conjugate
    (S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. 了解更多
  24. ALB-127158(a)

    Catalog No. A20211
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    MCH1 receptor antagonist
    ALB-127158(a) is a potent and selective melanin concentrating hormone 1 (MCH1) receptor antagonist. 了解更多
  25. Hispidol

    Catalog No. A20185
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    Hispidol ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 ?M. 了解更多
  26. Thalidomide-O-amido-C4-NH2

    Catalog No. A20184
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    E3 ligase ligand-linker conjugate
    Thalidomide-O-amido-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  27. Ziresovir

    Catalog No. A20179
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    RSV F protein inhibitor
    Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. 了解更多
  28. BLM-IN-1

    Catalog No. A20178
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    BLM inhibitor
    BLM-IN-1 (compound 29) is an effective Bloom syndrome protein (BLM) inhibitor, with a strong BLM binding KD of 1.81 μM and an IC50 of 0.95 μM for BLM. 了解更多
  29. ABT-072

    Catalog No. A20177
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    NS5B polymerase inhibitor
    ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus. 了解更多
  30. Wy 49051

    Catalog No. A20176
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    H1 receptor antagonist
    Wy 49051 is a potent, orally active H1 receptor antagonist, with IC50 of 44 nM. 了解更多
  31. SMS2-IN-1

    Catalog No. A20175
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    SMS2 inhibitor
    SMS2-IN-1 is a highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM. 了解更多
  32. Thalidomide-O-amido-C8-NH2

    Catalog No. A20174
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    Thalidomide-O-amido-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  33. Pyr3

    Catalog No. A20173
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    TRPC3 inhibitor
    Pyr3 is a selective inhibitor of transient receptor potential canonical channel 3 (TRPC3), with an IC50 of 700 nM for TRPC3-mediated Ca2+ influx. 了解更多
  34. FLT3-IN-3

    Catalog No. A20172
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    FLT3 inhibitor
    FLT3-IN-3 is a potent FLT3 inhibitor with IC50s of 13 and 8 nM for FLT3 WT and FLT3 D835Y, respectively. 了解更多
  35. MAT2A inhibitor 2

    Catalog No. A20171
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    MAT2A inhibitor
    MAT2A inhibitor 2 is a methionine adenosyltransferase 2A (MAT2A) inhibitor. 了解更多
  36. DC1

    Catalog No. A20170
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    DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. 了解更多
  37. GGsTop

    Catalog No. A20160
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    GGT inhibitor
    GGsTop (Nahlsgen) is a potent, non-toxic, highly selective and irreversible γ?glutamyl transpeptidase (GGT) inhibitor, with a Ki of 170 μM for Human GGT. 了解更多
  38. CU-CPT22

    Catalog No. A20148
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    TLR1/2 inhibitor
    CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor. 了解更多
  39. Letrazuril

    Catalog No. A20132
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    Letrazuril is an anti-HIV agent. 了解更多
  40. C-176

    Catalog No. A20121
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    mouse STING inhibitor
    C-176 is a strong and covalent mouse STING inhibitor. 了解更多
  41. Thalidomide-O-amido-C4-NH2 (TFA)

    Catalog No. A20120
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    E3 ligase ligand-linker conjugate
    Thalidomide-O-amido-C4-NH2 TFA (Cereblon Ligand-Linker Conjugates 6 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  42. CS-722 Free base

    Catalog No. A20119
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    CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex. 了解更多
  43. DAAO inhibitor-1

    Catalog No. A20117
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    DAAO inhibitor
    DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor with an IC50 of 0.12 μM. 了解更多
  44. dBET6

    Catalog No. A20110
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    BET degrader
    dBET6 is a highly potent, selective and cell-permeable degrader of BET based on PROTAC, with an IC50 of 14 nM, and has antitumor activity. 了解更多
  45. Furprofen

    Catalog No. A20107
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    Furprofen is an non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. Furprofen acts via the inhibition of prostaglandin (PGE) synthesis. Furprofen can be treated orally for the relief of pain. 了解更多
  46. CE3F4

    Catalog No. A20067
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    Epac1 antagonist
    CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), with IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively. 了解更多
  47. FITM

    Catalog No. A20047
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    mGlu1 receptor modulator
    FITM is a negative allosteric modulator of mGlu1 receptor with a Ki of 2.5 nM. 了解更多
  48. P-1075

    Catalog No. A20044
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    KATP channel activator
    P-1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6), with an EC50 value of 45 nM for SUR2B-KIR6 channel activation. 了解更多
  49. Branebrutinib

    Catalog No. A20043
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    BTK inhibitor
    Branebrutinib (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Bruton??s tyrosine kinase (BTK), with an IC50 of 0.1 nM. 了解更多
  50. DSP-1053

    Catalog No. A20037
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    SERT inhibitor
    DSP-1053 is a potent Serotonin Transporter (SERT) (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonistic activity. 了解更多

产品 201 到 250 共 2939个

每页
页面:
  1. 3
  2. 4
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  5. 7

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