Neuronal Signaling

产品 151 到 200 共 365个

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  1. CIQ

    Catalog No. A15523
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    NMDA receptors Potentiator
    CIQ是包含NR2C或NR2D亚基的NMDA受体的亚基选择性增强剂。 了解更多
  2. RO 25-6981 maleate

    Catalog No. A16083
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    NMDA receptors blocker
    RO 25-6981 maleate是含有NR2B亚基的NMDA受体的强效和选择性活性依赖性阻断剂。克隆的受体亚基组合NR1C/NR2B和NR1C/NR2A的IC50值分别为0.009和52 uM。 了解更多
  3. CNQX

    Catalog No. A16109
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    AMPA/kainate 拮抗剂
    CNQX是一种竞争性的非NMDA谷氨酸受体拮抗剂(AMPA和海藻酸酯受体的IC50分别为0.3和1.5 uM,而NMDA受体的IC50 = 25 uM)。 了解更多
  4. Ro 25-6981 maleate

    Catalog No. A13144
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    NMDA receptors Blocker
    Ro 25-6981是N-甲基-D-天冬氨酸(NMDA)受体的高亲和力,强效选择性阻断剂。 了解更多
  5. 7CKA

    Catalog No. A17070
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    NMDA receptor 拮抗剂
    7CKA是在甘氨酸位点起作用的NMDA受体拮抗剂。 了解更多
  6. D-AP5

    Catalog No. A17044
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    NMDA 拮抗剂
    D-AP5是一种选择性的N-甲基-D-天冬氨酸(NMDA)受体拮抗剂,可竞争性抑制NMDA受体的谷氨酸结合位点。 了解更多
  7. Neu-2000

    Catalog No. A17033
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    NMDA receptor 拮抗剂
    Neu-2000是可能用于治疗中风的NMDA受体拮抗剂。 了解更多
  8. Mephenesin

    Catalog No. A17493
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    NMDA receptor antagonist
    Mephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant. 了解更多
  9. Glycine

    Catalog No. A17936
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    NMDA antagonist
    AZD-4282, also known as aminoacetic acid and glycine, is a N-methyl-D-aspartate (NMDA) receptor antagonist potentially for the treatment of neuropathic pain. 了解更多
  10. GNE 0723

    Catalog No. A12757
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    NMDAR modulator
    GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. 了解更多
  11. Flupirtine maleate

    Catalog No. A10251
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    NMDA 拮抗剂
    Flupirtine maleate是Flupirine的盐形式,是一种非阿片类中枢性镇痛药,是一种选择性的神经元钾离子通道开放剂,也具有NMDA受体拮抗剂特性。 了解更多
  12. TCN 201

    Catalog No. A11947
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    NMDA Receptor 拮抗剂
    TCN 201是对NR1/NR2A相对于含NR1/NR2B的受体具有选择性的NMDA受体拮抗剂。 了解更多
  13. SDZ 220-581

    Catalog No. A12426
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    NMDA receptor 拮抗剂
    SDZ 220-581是一种竞争性NMDA受体拮抗剂(pKi = 7.7)。 了解更多
  14. NMDA

    Catalog No. A12751
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    NMDA receptor 激动剂
    NMDA是一种原型NMDA受体激动剂。 了解更多
  15. DNQX

    Catalog No. A13882
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    NMDA receptor 拮抗剂
    DNQX是一种非N-甲基-D-天冬氨酸(非NMDA)受体复合物拮抗剂。 了解更多
  16. (-)-MK 801 maleate

    Catalog No. A13435
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    NMDA receptor 拮抗剂.
    (-)-MK 801 maleate是一种有效的、选择性的、非竞争性的NMDA受体拮抗剂。它通过与NMDA相关离子通道内的一个位点结合而起作用。 了解更多
  17. SDZ 220-581 Ammonium salt

    Catalog No. A15235
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    NMDA receptor 拮抗剂
    SDZ 220-581 Ammonium salt是NMDA谷氨酸受体亚型(pKi = 7.7)的有效竞争性拮抗剂。 了解更多
  18. L-701324

    Catalog No. A15522
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    NMDA/glycine receptor 拮抗剂
    L-701324是一种活性且长效的抗惊厥药,对NMDA受体上的甘氨酸位点具有高亲和力和选择性。 了解更多
  19. (+)-MK 801 Maleate

    Catalog No. A12761
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    NMDA receptor 拮抗剂
    (+)-MK 801 Maleate是NMDA的有效拮抗剂,Ki值为30.5nM。 了解更多
  20. CGS19755

    Catalog No. A15791
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    NMDA 拮抗剂
    CGS 19755(顺式-4-膦酰基甲基-2-哌啶羧酸)是一种有效的立体定向抑制剂,由N-甲基-D-天冬氨酸(NMDA)诱发,但不是由KCl诱发的[3H]乙酰胆碱释放大鼠纹状体的切片。 了解更多
  21. Eliprodil

    Catalog No. A12946
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    NMDA 拮抗剂
    Eliprodil是一种非竞争性NR2B-NMDA受体拮抗剂(IC50 = 1 uM),对含NR2A和NR2C的受体效力较低(IC50> 100 uM)。 了解更多
  22. Sarcosine

    Catalog No. A16692
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    GlyT inhibitor/NMDA receptor
    Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site. 了解更多
  23. GV-196771A

    Catalog No. A13438
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    NMDA receptor antagonist
    GV-196771A is the sodium salt form of GV196771, is an NMDA receptor antagonist. 了解更多
  24. RPR104632

    Catalog No. A13385
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    NMDA receptor antagonist
    RPR104632 is a specific antagonist of NMDA receptor, with potent neuroprotective properties. 了解更多
  25. Ifenprodil tartrate

    Catalog No. A16583
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    NMDA receptor antagonist
    Ifenprodil tartrate is the atypical N-methyl-D-aspartate (NMDA) receptor antagonist, inhibits NMDA-induced currents at NR1A/NR2B receptors with high affinity (IC50 = 0.34 μM). 了解更多
  26. Transcrocetinate disodium

    Catalog No. A21051
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    NMDA receptor antagonist
    Transcrocetinate disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. 了解更多
  27. MDL 105519

    Catalog No. A21192
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    NMDA receptor antagonist
    MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor. 了解更多
  28. Radiprodil

    Catalog No. A21193
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    NMDA NR2B antagonist
    Radiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions. 了解更多
  29. NMDA-IN-1

    Catalog No. A21419
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    NMDA antagonist
    NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM. 了解更多
  30. 7-Chlorokynurenic acid sodium salt

    Catalog No. A21879
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    NMDA receptor antagonist
    7-Chlorokynurenic acid sodium salt is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 了解更多
  31. SDZ 220-581 hydrochloride, SDZ220-581, SDZ-220-581

    Catalog No. A21897
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    NMDA receptor antagonist
    SDZ 220-581 hydrochloride is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7. 了解更多
  32. Rislenemdaz

    Catalog No. A21907
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    NMDA receptor GluN2B antagonist
    Rislenemdaz (CERC-301) is an orally bioavailable and selective N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B) antagonist with Ki and IC50 of 8.1 nM and 3.6 nM, respectively. 了解更多
  33. Dihydromyricetin (Ampeloptin)

    Catalog No. A10252
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    Dihydropyrimidinase 抑制剂
    Dihydromyricetin (Ampeloptin)是具有良好性能的天然抗氧化剂。 了解更多
  34. Baicalin

    Catalog No. A10121
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    HIV-1 production 抑制剂
    Baicalin是已知的脯氨酰内肽酶抑制剂,并且影响GABA受体。 了解更多
  35. Nefiracetam (Translon)

    Catalog No. A10631
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    Nefiracetam (Translon)是认知增强剂。它激活L/N型钙通道,胆碱能,单胺能和GABA能系统。 了解更多
  36. SKF 89976A HCl

    Catalog No. A10849
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    GABA uptake 抑制剂
    SKF 89976A HCl是一种有效的GABA吸收抑制剂,hGAT-1,rGAT-2,hGAT-3和hBGT-1的IC50分别为0.13、550、944和7210μM。 了解更多
  37. Flumazenil

    Catalog No. A10397
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    Benzodiazepine 拮抗剂
    Flumazenil是竞争性抑制GABA/苯二氮卓受体复合物上苯二氮卓识别位点的活性。Flumazenil在一些活性动物模型中是弱部分激动剂,但在人类中很少或没有激动剂活性。 了解更多
  38. Furosemide

    Catalog No. A10412
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    Furosemide是GABAA受体的非竞争性拮抗剂,对含α6受体的选择性比含α1受体高约100倍。 了解更多
  39. Gabapentin

    Catalog No. A10413
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    Gabapentin (Neurontin)是一种药剂,特别是加巴类似物。 了解更多
  40. Gabapentin Hydrochloride

    Catalog No. A10414
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    Gabapentin Hydrochloride是一种加巴类似物。 了解更多
  41. Primidone (Mysoline)

    Catalog No. A10754
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    Primidone (Mysoline)是抗惊厥药。增强GABAA受体功能。 了解更多
  42. (+)-Bicuculline

    Catalog No. A12590
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    GABAA 拮抗剂
    (+)-Bicuculline是一种经典的GABAA拮抗剂。 了解更多
  43. Zaleplon

    Catalog No. A12993
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    Zaleplon是非苯二氮卓类药物,在苯二氮卓类部位起激动剂的作用。 了解更多
  44. AWD 131-138

    Catalog No. A13726
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    GABAA receptor 激动剂
    AWD 131-138是一种新的低亲和力的部分苯二氮卓类受体激动剂,在啮齿动物模型中具有强大的抗惊厥和抗焦虑特性。 了解更多
  45. 2-Hydroxysaclofen

    Catalog No. A13696
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    GABAB receptors 拮抗剂
    2-Hydroxysaclofen对GABAB受体是一种有效的选择性拮抗剂。 了解更多
  46. Bretazenil

    Catalog No. A13784
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    GABAA 激动剂
    Bretazenil,苯二氮卓类受体局部激动剂,可预防OP中毒。 了解更多
  47. Oxiracetam

    Catalog No. A14281
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    Oxiracetam是γ-氨基丁酸(GABA)的环状衍生物。 了解更多
  48. Cloflubicyne

    Catalog No. A13932
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    GABA 拮抗剂
    Cloflubicyne是一种有效的非竞争性GABA拮抗剂,惊厥药,实验室杀虫剂。 了解更多
  49. a5IA

    Catalog No. A14343
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    Benzodiazepine 激动剂
    a5IA是促智药物,它在GABAA受体的苯并二氮杂卓结合位点上起亚型选择性反向激动剂的作用。 了解更多
  50. RO 15-3890

    Catalog No. A14349
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    benzodiazepine receptor 拮抗剂
    Ro 15-1788是苯二氮卓受体拮抗剂。 了解更多

产品 151 到 200 共 365个

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