PPAR

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  1. Chiglitazar

    Catalog No. A12701
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    PPARα/γ dual agonist
    Chiglitazar is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively. 了解更多
  2. Leriglitazone

    Catalog No. A18636
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    PPAR gamma agonist
    Leriglitazone is a peroxisome proliferator activated receptor (PPAR) gamma agonist. 了解更多
  3. LJ570

    Catalog No. A20081
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    PPARα/PPARγ dual agonist
    LJ570 is a PPARα/PPARγ dual agonist with EC50s of 1.05 and 0.12 μM, respectively. 了解更多
  4. VCE-004.8

    Catalog No. A18549
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    PPARγ and CB2 receptor dual agonist
    VCE-004.8, a semi-synthetic multitarget cannabinoquinoid, is a specific PPARγ and CB2 receptor dual agonist with potent anti-inflammatory activity. 了解更多
  5. BR102375

    Catalog No. A18849
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    PPAR γ agonist
    BR102375 is a non-TZD peroxisome proliferator-activated receptor γ (PPAR γ) full agonist for the treatment of type 2 diabetes, reveals EC50 value of 0.28?μM and Amax ratio?of 98%. 了解更多
  6. Etofylline

    Catalog No. A17491
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    PPAR agonist
    Etofylline, also known as BRN-0251760, is a peroxisome proliferator-activated receptor (PPAR) agonist used to treat respiratory and cardiovascular disorders. Etofylline is often used as a bronchodilator. 了解更多
  7. Clofibric Acid

    Catalog No. A16463
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    PPARα 激动剂
    Clofibric Acid是PPARα激动剂和降血脂药。 了解更多
  8. Bezafibrate

    Catalog No. A16307
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    PPAR 激动剂
    Bezafibrate是首个经过临床测试的双重和泛PPAR共同激动剂。 了解更多
  9. Inolitazone dihydrochloride

    Catalog No. A15129
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    PPARγ 激动剂
    Inolitazone dihydrochloride是一种新型的高亲和力PPARγ激动剂,可激活PPARγ,其EC50约为罗格列酮的EC50,对RIE细胞无影响。 了解更多
  10. Rosiglitazone maleate

    Catalog No. A10809
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    PPAR 激动剂
    Rosiglitazone maleate是一种噻唑烷二酮类抗高血糖药,是PPARγ的高亲和、选择性的激动剂。 了解更多
  11. Pioglitazone (Actos)

    Catalog No. A11680
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    PPARγ 激动剂
    Pioglitazone (Actos)是选择性刺激核受体过氧化物酶体增殖物激活的受体γ(PPAR-γ),并在较小程度上刺激PPAR-α。 了解更多
  12. Rosiglitazone (BRL-49653)

    Catalog No. A10807
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    PPAR 激动剂
    Rosiglitazone (BRL-49653)是有效的降糖药,也是有效的噻唑烷二酮类胰岛素增敏剂,在大鼠,3T3-L1和人体脂肪细胞中IC50分别为12,4和9 nM。Rosiglitazone是PPAR-gamma的配体,对PPAR-alpha没有结合力。 了解更多
  13. Troglitazone

    Catalog No. A11981
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    PPARγ 激动剂
    Troglitazone是一种选择性PPARγ受体激动剂(鼠和人PPARγ受体的EC50值分别为780和555 nM)。 了解更多
  14. GW 7647

    Catalog No. A11982
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    PPARα 激动剂
    GW 7647是一种有效且高度选择性的PPARα激动剂(人PPARα,PPARγ和PPARδ受体的EC50值分别为6、1100和6200 nM)。 了解更多
  15. L-165,041

    Catalog No. A11983
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    PPARδ 激动剂
    L-165,041是有效的PPARδ激动剂(Ki = 6 nM);与其他亚型相比,对小鼠和人类PPARδ受体的选择性显示> 100倍。 了解更多
  16. pirinixic acid (WY 14643)

    Catalog No. A12360
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    PPARα 激动剂
    pirinixic acid (WY 14643)是一种高效pparα激动剂。 了解更多
  17. GW 501516

    Catalog No. A11437
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    PPARδ receptor 激动剂
    GW501516是一种合成pparδ特异性激动剂,对pparδ (ki=1.1 nm)显示出高亲和力,其选择性超过pparα和pparγ的1000倍。 了解更多
  18. Tesaglitazar

    Catalog No. A20891
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    PPAR alpha/gamma agonist
    Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively. 了解更多
  19. Fonadelpar

    Catalog No. A20848
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    PPARδ agonist
    Fonadelpar is a PPARδ agonist, used in the research of neuroparalytic keratopathy. 了解更多
  20. Arhalofenate

    Catalog No. A21135
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    PPARγ agonist
    Arhalofenate (MBX 102) is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes. 了解更多
  21. Pioglitazone hydrochloride

    Catalog No. A16670
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    PPARγ agonist
    Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. 了解更多
  22. 5-Aminosalicylic Acid

    Catalog No. A10570
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    PPARγ agonist
    5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 了解更多
  23. Indeglitazar

    Catalog No. A21148
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    PPAR agonist
    Indeglitazar is an orally available peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). 了解更多
  24. Inolitazone

    Catalog No. A21180
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    PPARγ agonist
    Inolitazone a novel high-affinity PPARγ agonist that is dependent upon PPARγ for its biological activity with IC50 of 0.8 nM for growth inhibition. 了解更多
  25. CDDO-Im

    Catalog No. A16308
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    PPARγ 激动剂
    CDDO-Im是一种新型的合成三萜,在体外和体内均比其母体化合物CDDO更有效。PPARγ激动剂。 了解更多
  26. Elafibranor

    Catalog No. A15454
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    PPAR 激动剂
    Elafibranor是过氧化物酶体增殖物激活的受体-α和-δ的激动剂,可诱导非酒精性脂肪性肝炎消退,而不会使纤维化恶化。 了解更多
  27. Aleglitazar

    Catalog No. A12492
    PPAR-α/γ 激动剂
    Aleglitazar是一种新型的双重PPAR-α/γ激动剂,IC50为2.8 nM/4.6 nM。 了解更多
  28. BMS-687453

    Catalog No. A15836
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    PPAR 激动剂
    BMS-687453是一种有效的选择性过氧化物酶体增殖物激活受体(PPAR)α激动剂,对人PPARα的EC(50)为10 nM,在PPAR-GAL4反式激活试验中,选择性是对人PPARgamma的410倍。 了解更多
  29. Balaglitazone

    Catalog No. A15013
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    PPAR-γ partial 激动剂
    Balaglitazone是PPAR-γ(γ)的新型局部激动剂。 了解更多
  30. GW1929

    Catalog No. A15099
    PPAR 激动剂
    GW1929是一种合成的过氧化物酶体增殖物激活受体-γ(PPARγ)激动剂,对人和人的IC50为6.2 nM和13 nM。 了解更多
  31. GW0742

    Catalog No. A14958
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    PPAR 激动剂
    GW0742是PPARδ的选择性激动剂,EC50值为1.1 nM。 了解更多

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