Membrane Transporters/Ion Channels

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  1. VX-770 (Ivacaftor)

    Catalog No. A10985
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    CFTR activator
    VX-770 (Ivacaftor)被称为CFTR增强剂,靶向作用于G551D-CFTR和F508del-CFTR,在fisher大鼠甲状腺细胞中EC50分别为100 nM和25 nM。 了解更多
  2. CK-1827452 (Omecamtiv mecarbil)

    Catalog No. A11206
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    Myosin activator
    CK-1827452 (Omecamtiv mecarbil)是选择性的心脏特异性肌球蛋白激活剂。 了解更多
  3. Bay K 8644

    Catalog No. A15875
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    Calcium Channel Activator
    Bay K 8644是一种有效的L型Ca2+通道选择性激活剂,IC50为17.3 nM。 了解更多
  4. ML277

    Catalog No. A21749
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    KCNQ1 potassium channel activator
    ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM. 了解更多
  5. NS-1643

    Catalog No. A15929
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    hERG channel activator
    NS-1643是一种人类以太相关基因(hERG)KV11.1通道激活剂(EC50 = 10.5 uM)。 了解更多
  6. RPR-260243

    Catalog No. A20977
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    HERG activator
    RPR-260243 is a novel activator of HERG; modifies HERG currents inhibited by dofetilide (IC50 = 58 nM); little effect on HERG current amplitude and no significant effects on steady-state activation parameters or on channel inactivation processes. 了解更多
  7. Nicorandil

    Catalog No. A10641
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    Kir6 (KATP) channel opener
    Nicorandil (SG-75) 钾离子通道活化剂。 了解更多
  8. NS 309

    Catalog No. A11934
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    KCa3.1 channel activator
    NS 309是小和中电导Ca2+激活的K+通道(KCa2和KCa3.1通道)的正调制器。 了解更多
  9. GW 542573X

    Catalog No. A13944
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    KCa2.1 channels activator
    GW 542573X是小电导Ca2+激活的K+通道(KCa2)的激活剂。 了解更多
    • 最新产品

    SKA-31

    Catalog No. A17117
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    potassium channel activator
    SKA-31是KCa2和KCa3.1钙激活钾通道的激活剂。 了解更多
  10. ICA-110381

    Catalog No. A15503
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    KV7.2/7.3 activator
    ICA-110381是KV7.2/7.3激活剂,EC50为0.38 uM。 了解更多
  11. NS1619

    Catalog No. A15975
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    Potassium channel activator
    NS1619是Bkca开启剂或大电导Ca2+激活的钾(BKCa,KCa1.1)通道激活剂。 了解更多
  12. KB130015

    Catalog No. A15493
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    hERG1 potassium channel activator
    KB130015是hERG1钾离子通道的新型激活剂,可在高压下阻断天然和重组hERG1通道,但在低压下激活它们。 了解更多
  13. Y-26763

    Catalog No. A12271
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    K+ (KATP) channel activator
    Y-26763 is a K+ channel opener and active metabolite of Y-27152. Y-26763 is an ATP-sensitive K+ (KATP) channel activator. 了解更多
  14. Eact

    Catalog No. A16179
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    CaCC activator
    Eact激活钙激活的氯离子通道(CaCC)TMEM16A CaCC。 了解更多
  15. SN 2

    Catalog No. A20839
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    TRPML3 ion channel activator
    SN 2 is a novel and potent activator of TRPML3 ion channel with EC50 of 1.8??0.13 μM. 了解更多
  16. Icilin

    Catalog No. A13560
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    TRPM8 and TRPA1 activator
    Icilin是一种冷却剂,可激活新型的冷受体TRPM8(CMR1)和TRPA1(ANKTM1/TRPN1),它们是TRP离子通道家族的成员。在表达CMR1的HEK 293细胞中感应电流(EC50 = 0.36μM)。 了解更多
  17. Cannabichromene

    Catalog No. A15497
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    TRPA1 activatior/TRPM8 blocker
    Cannabichromene是一种主要的非精神植物大麻素,可抑制内源性大麻素失活并激活瞬时受体电位锚蛋白1(TRPA1)。内源性大麻素和TRPA1均可调节肠胃蠕动。 了解更多
  18. Optovin

    Catalog No. A12932
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    photoactive TRPA1 activator
    Optovin是可逆光敏trpa1活化剂。 了解更多
  19. GSK1016790A

    Catalog No. A15854
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    TRPV4 Activator
    GSK1016790A是一种新型有效的TRPV4激活剂(瞬态受体电位香草酸4),在脉络丛上皮细胞中的EC50为34nM。 了解更多
  20. OAC2

    Catalog No. A15931
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    Oct4 activator
    OAC2是一种Oct4激活化合物,可通过Oct4基因启动子激活表达。 了解更多
  21. OAC1

    Catalog No. A12931
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    Oct4 Activator
    OAC1通过增强Oct4和Nanog驱动的基因表达来增强iPSC重编程效率。 了解更多

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