Pifithrin-alpha

目录号: A12451

p53 抑制剂

Pifithrin-alpha

Pifithrin-alpha Chemical Structure

CAS NO. 63208-82-2

Pifithrin-alpha是p53介导的细胞凋亡和p53依赖性基因转录(如细胞周期蛋白G,p21/waf1和mdm2表达)的可逆抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 350.00
10 mg
¥ 595.00
25 mg
¥ 1,400.00
50 mg
¥ 2,030.00
10mM * 1mL in DMSO
¥ 672.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Pifithrin-alpha是p53介导的细胞凋亡和p53依赖性基因转录(如细胞周期蛋白G,p21/waf1和mdm2表达)的可逆抑制剂。
靶点信息
p53
In vitro (25°C) DMSO 58 mg/mL (157.91 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+ 40% PEG 300+ 5%Tween80+ 50%ddH2O 3.46 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.23 mL 136.13 mL 272.26 mL
0.5 mM 5.45 mL 27.23 mL 54.45 mL
1 mM 2.72 mL 13.61 mL 27.23 mL
5 mM 0.54 mL 2.72 mL 5.45 mL

*The above data is based on the productmolecular weight 367.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12451
作用机制 Inhibitor (抑制剂)
M. Wt 367.3
Formula C16H18N2OS.HBr
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 63208-82-2
SMILES CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br

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