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搜索结果：“AZ 960”

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B-Raf inhibitor 1 dihydrochloride

Catalog No. A21834
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Raf kinase inhibitor

B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively. 了解更多

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RAF mutant-IN-1

Catalog No. A19011
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Raf nhibitor

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF340D/Y341D, B-RAFV600E and B-RAFWT, respectively. 了解更多

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ERK-IN-1

Catalog No. A19080
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RAF/ERK1/2 inhibitor

ERK-IN-1 (compound B) is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. 了解更多

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AZ304

Catalog No. A17225
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dual BRAF 抑制剂

AZ304 is a potent dual BRAF inhibitor targeting the kinase domains of wild type BRAF, V600E mutant BRAF. AZ304 exerted potent inhibitory effects on both wild type and V600E mutant forms of the serine/threonine-protein kinase BRAF, with IC50 values of 79?nM and 38?nM, respectively. 了解更多

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Diazepinomicin

Catalog No. A12891
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RAS/RAF/MAPK 抑制剂

Diazepinomicin，也称为TLN-4601，是具有潜在抗肿瘤活性的RAS/RAF/MAPK信号传导途径的小分子抑制剂。了解更多

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AZ628

Catalog No. A11063
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Raf 抑制剂

AZ628是一种RAF抑制剂，IC50值：BRAF V600E和野生型CRAF约为30 nM，野生型BRAF约为100 nM。了解更多

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