“Ligand-gated Ion Channels”的搜索结果

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  1. GSK2795039

    Catalog No. A20998
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    NOX2 inhibitor
    GSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell-free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 reduces apoptosis. 了解更多
  2. MD2-TLR4-IN-1

    Catalog No. A18452
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    MD2-TLR4 inhibitor
    MD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多
  3. Asymmetric dimethylarginine

    Catalog No. A18704
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    NOS inhibitor
    Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. 了解更多
  4. ML604086

    Catalog No. A18969
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    CCR8 抑制剂
    ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations. 了解更多
  5. GW-406381

    Catalog No. A19118
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    COX-2 inhibitor
    GW406381, a highly selective cyclooxygenase-2 (COX-2) inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury. 了解更多
  6. Deracoxib

    Catalog No. A18077
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    NSAID and COX-2 抑制剂
    Deracoxib is an NSAID and COX-2 inhibitor used to treat osteoarthritis. It induces cell cycle arrest and apoptosis in mammary tumor cells, decreases platelet aggregation, and lowers inflammatory responses. 了解更多
  7. PD1-PDL1 inhibitor 2

    Catalog No. A15906
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    PD-1/PD-L1 interaction 抑制剂
    PD1-PDL1 inhibitor 2 是PD-1/PD-L1相互作用抑制剂。 了解更多
  8. Apilimod

    Catalog No. A13794
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    IL-12/IL-23 inhibitor
    Apilimod is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS?Cstimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM. 了解更多

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