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搜索结果：“MK 1775”

“MK 1775”的搜索结果

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Raltegravir potassium

Catalog No. A21403
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integrase (IN) inhibitor

Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. 了解更多

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Vaniprevir

Catalog No. A11600
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HCV NS3/4A protease 抑制剂

Vaniprevir是丙型肝炎病毒（HCV）NS3/4A蛋白酶的非共价竞争性抑制剂。了解更多

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MK-5172 sodium salt

Catalog No. A15168
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HCV Protease 抑制剂

MK-5172 sodium salt是目前正在临床开发中的新型P2-P4喹喔啉大环HCV NS3/4a蛋白酶抑制剂。了解更多

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MK-5172 potassium salt

Catalog No. A15167
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HCV Protease 抑制剂

MK-5172 potassium salt是新型P2-P4喹喔啉大环HCV NS3/4a蛋白酶抑制剂。了解更多

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MK-5172 hydrate

Catalog No. A15166
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HCV Protease 抑制剂

MK-5172 hydrate是目前正在临床开发中的新型P2-P4喹喔啉大环HCV NS3/4a蛋白酶抑制剂。了解更多

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MK-5172

Catalog No. A13787
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HCV NS3/4a 抑制剂

MK-5172是丙型肝炎病毒NS3/4a蛋白酶的选择性抑制剂，在基因型和耐药变异中具有广泛的活性。了解更多

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MK 8742 (elbasvir)

Catalog No. A13965
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HCV NS5A 抑制剂

MK 8742 (elbasvir)是HCV NS5A抑制剂，是一种用于治疗HCV感染的全口服，无干扰素的治疗方案。了解更多

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Doravirine (MK-1439)

Catalog No. A12443
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NNRT 抑制剂

MK-1439是非核苷逆转录酶抑制剂。了解更多

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MK-2048

Catalog No. A11135
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HIV integrase 抑制剂

MK-2048是第二代整合酶抑制剂，旨在用于抵抗HIV感染。了解更多

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Raltegravir (MK-0518)

Catalog No. A10775
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HIV-1 integrase 抑制剂

Raltegravir (MK-0518)靶向整合酶，这是一种HIV酶，可将病毒遗传物质整合到人类染色体中，这是HIV发病机理中的关键步骤。了解更多

Product Citations (2)

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- Michal S Barski, .et al. Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures, Nat Commun, 2021, Aug 17;12(1):4996 PMID: 34404793
- Lea El Khoury, .et al. Spectrometric and computational studies of the binding of HIV-1 integrase inhibitors to viral DNA extremities, PeerJ Preprints, 2019, 7:e27833v1