“MK 1775”的搜索结果

产品 1 到 50 共 116个

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  1. MK-1775

    Catalog No. A10599
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    WEE1 抑制剂
    MK-1775是一种有效的体外和体内Wee1激酶抑制剂。 了解更多
  2. CaMKII-IN-1

    Catalog No. A21034
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    CaMKII inhibitor
    CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM. 了解更多
  3. MK-7145

    Catalog No. A21030
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    ROMK inhibitor
    MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM. 了解更多
  4. BMS-3

    Catalog No. A20999
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    LIMK inhibitor
    BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively. 了解更多
  5. Raltegravir potassium

    Catalog No. A21403
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    integrase (IN) inhibitor
    Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. 了解更多
  6. Niraparib R-enantiomer

    Catalog No. A21880
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    PARP1 inhibitor
    Niraparib R-enantiomer (MK-4827 R-enantiomer) is an excellent PARP1 inhibitor with IC50 of 2.4 nM. 了解更多
  7. Etoricoxib D4

    Catalog No. A21877
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    COX-2 inhibitor
    Etoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. 了解更多
  8. 1-Naphthyl PP1 hydrochloride

    Catalog No. A21790
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    Src/c-Abl inhibitor
    1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). 了解更多
  9. SRI 31215 TFA

    Catalog No. A21775
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    triplex matriptase inhibitor
    SRI 31215 (TFA), a triplex inhibitor of matriptase, hepsin and hepatocyte growth factor activator (HGFA) with IC50s of 0.69 μM, 0.65 μM, 0.3 μM, blocks pro-HGF activation and thus mimics the activity of HAI-1/2. 了解更多
  10. MK2-IN-1 hydrochloride

    Catalog No. A21662
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    MAPKAPK2(MK2) inhibitor
    MK2-IN-1 hydrochloride is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode. 了解更多
  11. MKC9989

    Catalog No. A21602
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    Hydroxy aryl aldehydes (HAA) inhibitor
    MKC9989 is a Hydroxy aryl aldehydes (HAA) inhibitor and also inhibits IRE1α with an IC50 of 0.23 to 44 μM. 了解更多
  12. MK-0674

    Catalog No. A21558
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    cathepsin K inhibitor
    MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S. 了解更多
  13. Finasteride acetate

    Catalog No. A21537
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    testosterone 5-alpha-reductase inhibitor
    Finasteride (acetate) is an orally active testosterone 5-alpha-reductase inhibitor. 了解更多
  14. VU591

    Catalog No. A21362
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    potassium channel inhibitor
    VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. 了解更多
  15. Amicarbazone

    Catalog No. A21294
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    photosynthetic electron transport inhibitor
    Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control. 了解更多
  16. Relebactam

    Catalog No. A21071
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    diazabicyclooctane inhibitor
    Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes. 了解更多
  17. Lisinopril

    Catalog No. A21064
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    angiotensin-converting enzyme inhibitor
    Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. 了解更多
  18. Niraparib hydrochloride

    Catalog No. A18018
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    PARP1 and PARP2 inhibitor
    Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. 了解更多
  19. Grazoprevir

    Catalog No. A17303
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    Hepatitis C virus NS3/4a protease inhibitor
    Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. 了解更多
  20. Niraparib tosylate

    Catalog No. A16618
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    PARP1/PARP2 inhibitor
    Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. 了解更多
  21. BOC-D-FMK

    Catalog No. A11356
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    caspase inhibitor
    Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 ?M. 了解更多
  22. MK-8998

    Catalog No. A12171
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    T-type calcium channel inhibitor
    MK-8998 (compound 33) is a potent and selective inhibitor of the T-type calcium channel. 了解更多
  23. MKC3946

    Catalog No. A12508
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    IRE1α inhibitor
    MKC3946 is a potent and soluble IRE1α inhibitor, used for cancer research. 了解更多
  24. Simvastatin

    Catalog No. A10845
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    HMG-CoA reductase inhibitor
    Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. 了解更多
  25. CMK

    Catalog No. A11368
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    RSK2 kinase inhibitor
    CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. 了解更多
  26. T56-LIMKi

    Catalog No. A12266
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    LIMK2 inhibitor
    T56-LIMKi is a selective inhibitor of LIMK2; inhibits the growth of Panc-1 cells with an IC50 of 35.2 μM. 了解更多
  27. SDZ-MKS 492

    Catalog No. A12283
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    cyclic nucleotide phosphodiesterase inhibitor
    SDZ-MKS 492 (MKS 492) is a selective type III isozyme inhibitor of cyclic nucleotide phosphodiesterase, effective in allergic bronchoconstriction and platelet activating factor (PAF) or LTB4-induced inflammatory reactions in animals. 了解更多
  28. FMK 9a

    Catalog No. A12603
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    autophagin-1 inhibitor
    FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay. 了解更多
  29. MK-8617

    Catalog No. A12618
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    pan HIF PHD1-3 inhibitor
    MK-8617 is an orally active pan-inhibitor of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) with an IC50 of 1 nM for PHD2. 了解更多
  30. MK-2 Inhibitor III

    Catalog No. A13608
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    MAPKAP-K2 (MK-2) inhibitor
    MK-2 Inhibitor III (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC50 of 0.85 nM. 了解更多
  31. PT2977

    Catalog No. A18465
    HIF-2alpha inhibitor
    PT2977 is HIF-2alpha inhibitor with an IC50 of 9 nM. 了解更多
  32. R-10015

    Catalog No. A18806
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    LIMK inhibitor
    R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1. 了解更多
  33. MK-8719

    Catalog No. A18839
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    OGA inhibitor
    MK-8719 is a highly potent and selective OGA inhibitor (EC50 = 52.7 nM) which is a Potential Treatment for Tauopathies. MK-8719 showed excellent CNS penetration that has been advanced to first-in-human phase I clinical trials. 了解更多
  34. L-(-)-α-Methyldopa (hydrate)

    Catalog No. A18111
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    DOPA decarboxylase inhibitor
    Methyldopa Sesquihydrate is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. 了解更多
  35. Elbasvir (MK-8742)

    Catalog No. A16855
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    NS5A 抑制剂
    Elbasvir (MK-8742)是一种NS5A抑制剂,可预防丙型肝炎病毒RNA复制和病毒体组装。根据基因型,EC50的中值范围为0.2至3600 pmol/L。 了解更多
  36. MK-8353 (SCH900353)

    Catalog No. A16838
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    ERK 抑制剂
    MK-8353 (SCH900353)是一种口服生物利用型,选择性和有效的ERK抑制剂,在体外抑制激活的ERK1和ERK2,IC50值分别为23.0 nM和8.8 nM(IMAP激酶测定),以及未激活的ERK2,具有IC50值 0.5 nM(MEK1-ERK2耦合测定)。 了解更多
  37. BMS-5

    Catalog No. A12839
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    LIMK 抑制剂
    BMS-5是一种有效的LIMK抑制剂,对LIMK1和LIMK2的IC50分别为7 nM和8 nM。 了解更多
  38. Z-FA-FMK

    Catalog No. A16381
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    Cysteine protease 抑制剂
    Z-FA-FMK是半胱氨酸蛋白酶的不可逆抑制剂。 了解更多
  39. STO-609 acetate

    Catalog No. A16345
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    CaMKK 抑制剂
    STO-609是钙/钙调蛋白依赖性激酶激酶(CaMKK)亚型CaMKKα和CaMKKβ(Ki分别为80和15 ng/ml)的细胞渗透性抑制剂。 了解更多
  40. Z-VAD(OH)-FMK

    Catalog No. A16340
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    Caspase 抑制剂
    Z-VAD(OH)-FMK是所有胱天蛋白酶的不可逆三肽抑制剂。 了解更多
  41. Z-YVAD-FMK

    Catalog No. A16317
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    Caspase-1 抑制剂
    Z-YVAD-FMK是有效的细胞渗透性和caspase-1不可逆抑制剂。 了解更多
  42. LX7101

    Catalog No. A16211
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    LIMK2 抑制剂
    LX7101是基于吡咯并嘧啶的局部递送的LIM域激酶2(LIMK2)抑制剂,LIM域激酶2是与眼内压调节相关的激酶。 了解更多
  43. Diflunisal

    Catalog No. A16166
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    COX 抑制剂
    Diflunisal是具有止痛和抗炎活性的水杨酸衍生物。 了解更多
  44. Verubecestat (MK-8931)

    Catalog No. A16113
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    β-secretase/BACE1 抑制剂
    Verubecestat (MK-8931)是一种有效的选择性β-分泌酶抑制剂,是BACE1蛋白抑制剂或Beta-site APP裂解酶1抑制剂。 了解更多
  45. MK-4101

    Catalog No. A16111
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    Hedgehog 抑制剂
    MK-4101是Hedgehog通路的有效和选择性抑制剂。 了解更多
  46. DTP3

    Catalog No. A16059
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    JNK 抑制剂
    DTP3是选择性GADD45β/ MKK7抑制剂,可抑制癌症选择性NF-kB生存途径。 了解更多
  47. PPACK

    Catalog No. A16048
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    Thrombin 抑制剂
    PPACK 是一种有效,选择性和不可逆的凝血酶抑制剂,Ki值为0.24 nM。 了解更多
  48. CMPD-1

    Catalog No. A16040
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    p38 MAPK 抑制剂
    CMPD-1是p38α介导的MK2a(促分裂原激活的蛋白激酶2a)磷酸化(表观Ki = 330 nM)的非ATP竞争性选择性抑制剂。 了解更多
  49. Decanoyl-RVKR-CMK

    Catalog No. A16027
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    Proprotein convertases 抑制剂
    Decanoyl-RVKR-CMK是一种选择性,不可逆且可渗透细胞的前蛋白转化酶竞争性抑制剂。 了解更多
  50. Z-IETD-FMK

    Catalog No. A12800
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    caspase 8 抑制剂
    Z-IETD-FMK是caspase 8的特异性抑制剂。 了解更多

产品 1 到 50 共 116个

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