“glucagon receptor”的搜索结果

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  1. Bexarotene (LGD1069)

    Catalog No. A11094
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    Retinoid X Receptor Ligand
    Bexarotene (LGD1069)是一种高度选择性的类维生素A X受体(RXR)激动剂。 了解更多
  2. Cyproterone acetate

    Catalog No. A11409
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    Androgen Receptor 拮抗剂
    Cyproterone acetate是17-羟孕酮的合成衍生物,可作为雄激素受体拮抗剂以及具有弱孕激素和糖皮质激素活性的弱孕激素受体激动剂。 了解更多
  3. Aminophylline

    Catalog No. A10066
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    Adenosine receptor 拮抗剂
    Aminophylline是一种非选择性的腺苷受体拮抗剂和磷酸二酯酶抑制剂,能够逆转局部缺血引起的bradyasystole。 了解更多
  4. Dyphylline

    Catalog No. A10339
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    Adenosine receptor 拮抗剂
    Dyphylline是黄嘌呤衍生物,具有支气管扩张药和血管扩张药的作用。 它充当腺苷受体拮抗剂和磷酸二酯酶抑制剂。 了解更多
  5. GW 501516

    Catalog No. A11437
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    PPARδ receptor 激动剂
    GW501516是一种合成pparδ特异性激动剂,对pparδ (ki=1.1 nm)显示出高亲和力,其选择性超过pparα和pparγ的1000倍。 了解更多
  6. GW3965

    Catalog No. A15100
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  7. Etofylline

    Catalog No. A17491
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    PPAR agonist
    Etofylline, also known as BRN-0251760, is a peroxisome proliferator-activated receptor (PPAR) agonist used to treat respiratory and cardiovascular disorders. Etofylline is often used as a bronchodilator. 了解更多
  8. Molindone hydrochloride

    Catalog No. A17647
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    MAO inhibitor
    Molindone HCl is a D2 dopamine receptor antagonist. It also acts as a MAO inhibitor. 了解更多
  9. BR102375

    Catalog No. A18849
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    PPAR γ agonist
    BR102375 is a non-TZD peroxisome proliferator-activated receptor γ (PPAR γ) full agonist for the treatment of type 2 diabetes, reveals EC50 value of 0.28?μM and Amax ratio?of 98%. 了解更多
  10. NXT629

    Catalog No. A18771
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    PPAR-α antagonist
    NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. 了解更多
  11. MA-0204

    Catalog No. A19031
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    PPARδ modulator
    MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD). 了解更多
  12. WYC-209

    Catalog No. A19001
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    RAR agonist
    WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. 了解更多
  13. Leriglitazone

    Catalog No. A18636
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    PPAR gamma agonist
    Leriglitazone is a peroxisome proliferator activated receptor (PPAR) gamma agonist. 了解更多
  14. Cilofexor

    Catalog No. A13143
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    FXR agonist
    Cilofexor (GS-9674) is a farnesoid X receptor (FXR) agonist. 了解更多
  15. Nidufexor

    Catalog No. A12625
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    FXR agonist
    Nidufexor is a farnesoid X receptor (FXR) agonist. 了解更多
  16. GNF351

    Catalog No. A12609
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    AHR antagonist
    GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. 了解更多
  17. ITE

    Catalog No. A12565
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    AhR agonist
    ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM. ITE also has immunosuppressive activity. 了解更多
  18. Tesaglitazar

    Catalog No. A20891
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    PPAR alpha/gamma agonist
    Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively. 了解更多
  19. Arhalofenate

    Catalog No. A21135
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    PPARγ agonist
    Arhalofenate (MBX 102) is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes. 了解更多
  20. Indeglitazar

    Catalog No. A21148
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    PPAR agonist
    Indeglitazar is an orally available peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). 了解更多
  21. FICZ

    Catalog No. A21452
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    AhR agonist
    FICZ is a potent aryl hydrocarbon receptor (AhR) agonist with a Kd of 70 pM. 了解更多
  22. INT-767

    Catalog No. A21494
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    dual FXR/TGR5 agonist
    INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively. 了解更多
  23. RGX-104 free Acid

    Catalog No. A21513
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    LXR agonist
    RGX-104 free Acid is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. 了解更多
  24. Fexaramine

    Catalog No. A21771
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    FXR agonist
    Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity relative to natural compounds. 了解更多
  25. Leptomycin B

    Catalog No. A20985
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    nuclear export receptor CRM1 inhibitor
    Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle. 了解更多
  26. Rovazolac

    Catalog No. A18354
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    liver x receptor (LXR) modulator
    Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1. 了解更多
  27. VCE-004.8

    Catalog No. A18549
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    PPARγ and CB2 receptor dual agonist
    VCE-004.8, a semi-synthetic multitarget cannabinoquinoid, is a specific PPARγ and CB2 receptor dual agonist with potent anti-inflammatory activity. 了解更多
  28. AC-55649

    Catalog No. A20078
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    Human RARβ2 receptor agonist
    AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9. 了解更多
  29. GW3965 HCl

    Catalog No. A11204
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    LXR-like receptors 激动剂
    GW3965 HCl是一种选择性的口服活性肝X受体(LXR)完全激动剂。 了解更多
  30. ITI214

    Catalog No. A21422
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    PDE1 inhibitor
    ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). 了解更多
  31. ITI214 free base

    Catalog No. A21947
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    picomolar PDE1 inhibitor
    ITI-214 (free base) is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). 了解更多

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