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cis-Pralsetinib
Catalog No. A21586 RET inhibitorcis-Pralsetinib (cis-BLU-667) is a highly potent and selective inhibitor of rearranged during transfection (RET), with IC50s ranging from 0.3 to 0.4 nM for WT RET and four enzyme variants (V804L, V804M, M918T, CCDC6-RET), and with broad, robust and anti-tumor activity against multiple RET-driven solid tumor types. 了解更多 -
(S)-Gossypol acetic acid
Catalog No. A16323 (S)-Gossypol acetic acid是Bcl-2的抑制剂，在过表达Bcl-2（IC50，18.1μM）或Bcl-xL（IC50，22.9μM）的Jurkat细胞中有效诱导细胞死亡。 了解更多 -
Necrostatin 2 racemate
Catalog No. A15327 -
p53 and MDM2 proteins-interaction-inhibitor racemic
Catalog No. A15202 -
Acetate gossypol
Catalog No. A14795 -
Homoharringtonine
Catalog No. A14490 Stat3 抑制剂 & Apoptosis inducer同型harringtonine是一种头孢他辛生物碱，可抑制肝核糖体中二苯丙氨酸和乙酰苯丙氨酰嘌呤霉素的形成。 了解更多 -
AT101 acetic acid
Catalog No. A13578 pan Bcl-2 抑制剂AT101 acetic acid对映体AT101与Bcl-2，Bcl-xL和Mcl-1结合，Ki分别为0.32μM，0.48μM和0.18μM；不抑制BIR3域和BID。 了解更多 -
Jaceosidin
Catalog No. A12080 Jaceosidin是一种来源于艾蒿的药理活性黄酮，通过阻断培养的人乳腺上皮细胞中erk-1和-2的磷酸化来抑制佛波酯诱导的cox-2和MMP-9的上调。 了解更多
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