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TAK-960 hydrochloride
Catalog No. A21703 PLK1 inhibitorTAK-960 hydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM at 10 μM ATP; TAK-960 hydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. 了解更多 -
TAK-220
Catalog No. A20618 -
TAK-700 Salt (Orteronel Salt)
Catalog No. A13515 CYP17A1/androgen synthesis 抑制剂TAK-700 Salt (Orteronel Salt)是一种雄激素合成抑制剂。它选择性地抑制在睾丸，肾上腺和前列腺肿瘤组织中表达的酶CYP17A。 了解更多 -
TAK-242 S enantiomer
Catalog No. A15253 TLR4 抑制剂TAK-242的S对映体。TAK-242（Resatorvid），Toll样受体（TLR）4信号转导的小分子抑制剂。TAK-242用于治疗败血症和败血性休克。 了解更多 -
Letaxaban (TAK-442)
Catalog No. A12871 factor Xa 抑制剂Letaxaban (TAK-442)是一种有效的，选择性的，口服活性的Xa抑制剂，是一种四氢嘧啶-2（1H）-衍生物。TAK-442在贫血小板的人[半最大抑制浓度（IC（50））：53 nM，TAK-442]和大鼠（IC（50）：32 nM，TAK-442）血浆中抑制内源性FXa活性。 了解更多
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