“rasgap ras p21”的搜索结果

产品 201 到 250 共 1051个

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  1. 1,2,3,6-Tetragalloylglucose

    Catalog No. A19802
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    UGT1A1 inhibitor
    1,2,3,6-Tetragalloylglucose is a potent UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) inhibitor, with a Ki of 1.68 μM. 了解更多
  2. Fluensulfone

    Catalog No. A19788
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    Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes. 了解更多
  3. Nampt-IN-3

    Catalog No. A19769
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    NAMPT inhibitor
    Nampt-IN-3 (Compound 35) simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. Nampt-IN-3 effectively induces cell apoptosis and autophagy and ultimately leads to cell death. 了解更多
  4. Tibenelast sodium

    Catalog No. A19756
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    phosphodiesterase inhibitor
    Tibenelast sodium is a phosphodiesterase inhibitor. 了解更多
  5. LLY-283

    Catalog No. A19754
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    PRMT5 inhibitor
    LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity. 了解更多
  6. PF-9366

    Catalog No. A19743
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    Mat2A inhibitor
    PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC50 of 420 nM and a Kd of 170 nM. 了解更多
  7. KDM2A/7A-IN-1

    Catalog No. A19724
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    KDM2A/7A inhibitor
    KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16?μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases. 了解更多
  8. GeA-69

    Catalog No. A19705
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    PARP14 inhibitor
    GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 ?M. 了解更多
  9. 5-Methoxyflavone

    Catalog No. A19698
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    DNA polymerase-beta inhibitor
    5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. 了解更多
  10. RO-7

    Catalog No. A19695
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    PA endonuclease inhibitor
    RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses. 了解更多
  11. HIV-1 integrase inhibitor 3

    Catalog No. A19628
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    INST inhibitor
    HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. 了解更多
  12. HIV-1 integrase inhibitor 4

    Catalog No. A19617
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    INST inhibitor
    HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. 了解更多
  13. SNIPER(BRD)-1

    Catalog No. A19579
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    SNIPER inhibitor
    SNIPER(BRD4)-1 is a specific and nongenetic inhibitor of apoptosis protein (IAP)-dependent protein eraser (SNIPER) which acts as a protein degradation inducer of bromodomain-containing protein 4 (BRD4). 了解更多
  14. Macropa-NH2

    Catalog No. A19561
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    Macropa-NH2 is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases. 了解更多
  15. GSTO1-IN-1

    Catalog No. A19530
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    GSTO1 inhibitor
    GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50 of 31 nM. 了解更多
  16. EZM 2302

    Catalog No. A19484
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    CARM1 inhibitor
    EZM 2302 is an inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1) with an IC50 of 6?nM. 了解更多
  17. WAY127093B racemate

    Catalog No. A19474
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    PDE-4 inhibitor
    WAY127093B racemate is the racemate of WAY127093B. WAY127093B is a novel, orallyactive phosphodiesterase IV inhibitor in guinea pigs and rats. 了解更多
  18. Sinefungin

    Catalog No. A19473
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    virion mRNA(guanine-7-)-methyltransferase inhibitor
    Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. 了解更多
  19. 3-Methyltoxoflavin

    Catalog No. A19466
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    PDI inhibitor
    3-Methyltoxoflavin is a potent Protein disulfide isomerase (PDI) inhibitor, with an IC50 of 170 nM. 了解更多
  20. Lith-O-Asp

    Catalog No. A19397
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    ST inhibitor
    Lith-O-Asp is a sialytransferase (ST) inhibitor, with IC50s of 12-37 μM. 了解更多
  21. Lodenafil carbonate

    Catalog No. A19350
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    PDE5 inhibitor
    Lodenafil carbonate, a dimer that acts as a prodrug delivering Lodenafil in vivo, is an orally active phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED). 了解更多
  22. Calmidazolium chloride

    Catalog No. A19306
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    CaMK antagonist
    Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively. Also in anti-cancer research. Calmidazolium binds to CaMK with a Kd of 3 nM. 了解更多
  23. Macropa-NCS

    Catalog No. A19293
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    Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070. A promising therapeutic radionuclide applied in the treatment of soft-tissue metastases. 了解更多
  24. Gadopentetic acid

    Catalog No. A19262
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    paramagnetic contrast agent
    Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies. The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI. 了解更多
  25. Symetine

    Catalog No. A19232
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    Symetine is an antiparasitic and antispirochete agent. 了解更多
  26. Sultiame

    Catalog No. A19218
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    carbonic anhydrase inhibitor
    Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic drug. 了解更多
  27. ABL127

    Catalog No. A19208
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    PME-1 inhibitor
    ABL127 is a selective and covalent inhibitor of protein methylesterase 1 (PME-1) with IC50s of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively. 了解更多
  28. SCD1 inhibitor-1

    Catalog No. A19205
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    SCD1 inhibitor
    SCD1 inhibitor-1 is a potent and liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitor. 了解更多
  29. SGN-2FF

    Catalog No. A19196
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    fucosylation inhibitor
    SGN-2FF is an oral inhibitor of fucosylation, directly inhibits fucosyltransferase activity, and possesses antitumor activity. 了解更多
  30. J22352

    Catalog No. A19174
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    HDAC6 inhibitor
    J22352 is a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM. 了解更多
  31. Nicotinic acid mononucleotide

    Catalog No. A19173
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    Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase. 了解更多
  32. MRTX849

    Catalog No. A16482
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    KRAS G12C inhibitor
    MRTX849 is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. 了解更多
  33. N-Desethyl amodiaquine dihydrochloride

    Catalog No. A21695
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    N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. 了解更多
  34. Banoxantrone D12

    Catalog No. A21443
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    Banoxantrone D12 (AQ4N D12) is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. 了解更多
  35. Banoxantrone D12 dihydrochloride

    Catalog No. A21438
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    Banoxantrone D12 dihydrochloride (AQ4N D12 dihydrochloride) is the deuterium labeled banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. 了解更多
  36. Banoxantrone dihydrochloride

    Catalog No. A21432
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    Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. 了解更多
  37. Fexinidazole

    Catalog No. A21274
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    Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei. 了解更多
  38. (S)-Rasagiline

    Catalog No. A21272
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    (S)-Rasagiline (TVP1022) is the S-isomer of Rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. 了解更多
  39. YF-2

    Catalog No. A21018
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    histone acetyltransferase activator
    YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease. 了解更多
  40. (±)-Huperzine A

    Catalog No. A21003
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    AChE inhibitor
    (??)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). 了解更多
  41. (+)-Phenserine

    Catalog No. A20993
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    cholinesterase noncompetitive inhibitor
    (+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM. 了解更多
  42. Ilorasertib

    Catalog No. A20982
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    ATP-competitive multitargeted kinase inhibitor
    Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively. 了解更多
  43. Indotecan

    Catalog No. A20979
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    Top1 inhibitor
    Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. 了解更多
  44. MF-438

    Catalog No. A20963
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    SCD1 inhibitor
    MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1. 了解更多
  45. BMS-214662

    Catalog No. A20948
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    farnesyl transferase inhibitor
    BMS-214662 is a potent and selective farnesyl transferase inhibitor with potent antitumor activity with an IC50 of 1.35 nM. 了解更多
  46. Remodelin

    Catalog No. A21985
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    acetyl-transferase protein NAT10 inhibitor
    Remodelin is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. 了解更多
  47. Raltegravir potassium

    Catalog No. A21403
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    integrase (IN) inhibitor
    Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. 了解更多
  48. BTZ043

    Catalog No. A21263
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    DprE1 inhibitor
    BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively. 了解更多
  49. Carotegrast

    Catalog No. A21997
    α4 integrin receptor inhibitor
    Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities. 了解更多
  50. Ziprasidone D8

    Catalog No. A21989
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    5-HT / dopamine receptor antagonist
    Ziprasidone D8 is deuterium labeled Ziprasidone, which is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多

产品 201 到 250 共 1051个

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页面:
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  2. 4
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