“Ligand-gated Ion Channel”的搜索结果

产品 51 到 100 共 2046个

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  1. Fantofarone

    Catalog No. A19316
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    Calcium Channel antagonist
    Fantofarone is a highly potent Calcium Channel antagonist. 了解更多
  2. Dantrolene sodium

    Catalog No. A17644
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    Calcium channel proteins inhibitor
    Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. 了解更多
  3. Ralfinamide mesylate

    Catalog No. A22002
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    Na+ channel blocker
    Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain. 了解更多
  4. ML277

    Catalog No. A21749
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    KCNQ1 potassium channel activator
    ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM. 了解更多
  5. TTA-Q6(isomer)

    Catalog No. A21724
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    T-type Ca2+ channel antagonist
    TTA-Q6(isomer) is an isomer of TTA-Q6. TTA-Q6 is a selective T-type Ca2+ channel antagonist. 了解更多
  6. EIPA hydrochloride

    Catalog No. A21441
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    TRPP3 channel inhibitor
    EIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also inhibits Na+/H+-exchanger (NHE) and macropinocytosis. 了解更多
  7. Efonidipine hydrochloride

    Catalog No. A21431
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    dual T-type and L-type calcium channel blocker
    Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB). 了解更多
  8. Levamlodipine besylate

    Catalog No. A21418
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    Calcium channel blocker
    Levamlodipine besylate ((S)-Amlodipine besylate) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina. 了解更多
  9. VU591

    Catalog No. A21362
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    potassium channel inhibitor
    VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. 了解更多
  10. TTA-Q6

    Catalog No. A21360
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    T-type Ca2+ channel antagonist
    TTA-Q6 is a selective T-type Ca2+ channel antagonist, used in the neurological disease. 了解更多
  11. Cisapride

    Catalog No. A21340
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    hERG potassium channel inhibitor
    Cisapride(R 51619) is a nonselective 5-HT4 receptor agonist, it is also a potent hERG potassium channel inhibitor. 了解更多
  12. Funapide

    Catalog No. A21298
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    Sodium Channel Nav1.7 inhibitor
    Funapide (TV 45070; XEN402) is a potent Sodium Channel Nav1.7 inhibitor. 了解更多
  13. (S)-(-)-Bay-K-8644

    Catalog No. A21164
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    L-type Ca2+ channel agonist
    (S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. (S)-(-)-Bay-K-8644 activates Ba2+ currents (IBa) (EC50=32 nM). 了解更多
  14. Bay-K-8644 ((R)-(+)-)

    Catalog No. A21163
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    calcium channel inhibitor
    Bay-K-8644 (R)-(+)- is a calcium channel inhibitor. Bay-K-8644 (R)-(+)- inhibits Ba2+ currents (IBa) (IC50=975 nM). 了解更多
  15. Carboxyamidotriazole

    Catalog No. A20940
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    non-voltage dependent calcium channel blocker
    Carboxyamidotriazole (L 651582) is a blocker of non-voltage dependent calcium channel. 了解更多
  16. Efonidipine hydrochloride monoethanolate

    Catalog No. A18030
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    dual T-type and L-type calcium channel blocker
    Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB). 了解更多
  17. Nicardipine hydrochloride

    Catalog No. A16634
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    calcium channel blocker
    Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. 了解更多
  18. Nav1.7-IN-3

    Catalog No. A13626
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    voltage-gated sodium channel Nav1.7 inhibitor
    Nav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration. 了解更多
  19. SKF-96365 hydrochloride

    Catalog No. A16706
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    TRP Channel blocker
    SKF-96365 hydrochloride is a non-selective TRP Channel blocker. 了解更多
  20. Amlodipine aspartic acid impurity

    Catalog No. A13264
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    calcium channel blocker
    Amlodipine aspartic acid impurity is the impurity of Amlodipine aspartic acid. Amlodipine aspartic acid is a calcium channel blocker with antihypertensive and antianginal properties. 了解更多
  21. MK-8998

    Catalog No. A12171
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    T-type calcium channel inhibitor
    MK-8998 (compound 33) is a potent and selective inhibitor of the T-type calcium channel. 了解更多
  22. Nisoldipine

    Catalog No. A10646
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    calcium channel blocker
    Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. 了解更多
  23. ABT-639 hydrochloride

    Catalog No. A12571
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    T-type Ca2+ channel blocker
    ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker. 了解更多
  24. ICA

    Catalog No. A13062
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    SK channel inhibitor
    ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 ?M. 了解更多
  25. Mibefradil

    Catalog No. A12478
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    Calcium channel blocker
    Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively. 了解更多
  26. ABT-639

    Catalog No. A12330
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    T-type Ca2+ channel blocker
    ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. 了解更多
  27. Sipatrigine

    Catalog No. A12943
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    neuroprotective agent
    Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke. 了解更多
  28. Metaflumizone

    Catalog No. A18830
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    Sodium channel blocker
    Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker. 了解更多
  29. Bepridil hydrochloride

    Catalog No. A18016
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    calcium channel blocker
    Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity. 了解更多
  30. Senicapoc (ICA-17043)

    Catalog No. A11568
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    Gardos channel blocker
    Senicapoc (ICA-17043) is a potent and selective Gardos channel blocker with IC50 value of 11 nM. It blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM. 了解更多
  31. Dooku1

    Catalog No. A18409
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    Piezo1 channel antagonist
    Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. 了解更多
  32. Aranidipine

    Catalog No. A18291
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    Calcium channel antagonist
    Aranidipine (MPC1304) is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects. 了解更多
  33. Lercanidipine

    Catalog No. A17787
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    Calcium channel blocker
    Lercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. This lowers the blood pressure and allows the heart to work more efficiently. 了解更多
  34. Fendiline hydrochloride

    Catalog No. A17575
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    Calcium channel blocker
    Fendiline hydrochloride is a nonselective calcium channel blocker. 了解更多
  35. Nicardipine

    Catalog No. A17571
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    Calcium channel blockers
    Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. 了解更多
  36. 4-Aminopyridine

    Catalog No. A17490
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    Potassium channel blocker
    Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. 了解更多
  37. Efonidipine

    Catalog No. A17478
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    Calcium channel blocker
    Efonidipine is a dihydropyridine calcium channel blocker that blocks both T-type and L-type calcium channels. It has also been studied in atherosclerosis and acute renal failure. 了解更多
  38. Glyburide

    Catalog No. A10433
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    K+ channel and CFTR Cl- channel blocker
    Glyburide (Glibenclamide) 是一种抗糖尿病化合物,是一类磺脲类药物。 了解更多
  39. Guanosine 5'-triphosphate trisodium salt

    Catalog No. A18283
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    Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) is an activator of signal transduction of G proteins. 了解更多
  40. Auranofin

    Catalog No. A18996
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    Auranofin is a gold salt classified by the World Health Organization as an antirheumatic agent. It is a gold-thiol complex with anti-inflammatory and immunosuppressive actions. 了解更多
  41. Triphala

    Catalog No. A16067
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    Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities
    Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica. Triphala inhibits NF-κB activation. Triphala exerts antifungal action. Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities. 了解更多
  42. Adenosine deaminase

    Catalog No. A19330
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    Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. 了解更多
  43. Thrombin

    Catalog No. A18861
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    digest GST-tagged proteins
    Thrombin is a trypsin-like allosteric serine protease. Thrombin enables site-specific cleavage of fusion proteins with an accessible Thrombin recognition sequence and can be used to digest GST-tagged proteins. 了解更多
  44. Melanin

    Catalog No. A19576
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    unique pigment
    Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. 了解更多
  45. HM-43239

    Catalog No. A20826
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    FLT3 inhibitor
    HM-43239 is a Novel Potent Small Molecule FLT3 Inhibitor, in Acute Myeloid Leukemia (AML) with FMS-like Tyrosine Kinase 3 (FLT3) Mutations 了解更多
  46. Cinnamylamine

    Catalog No. A20835
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    Cinnamylamine can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. 了解更多
  47. Peptide 401

    Catalog No. A13913
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    Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT). 了解更多
  48. BMVC-8C3O

    Catalog No. A22052
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    DNA G-quadruplexe (G4) ligand
    BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s. 了解更多
  49. TLR4-IN-C34

    Catalog No. A22057
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    TLR4 inhibitor
    TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. 了解更多
  50. BMS-1001

    Catalog No. A22061
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    PD-1/PD-L1 interaction inhibitor
    BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. 了解更多

产品 51 到 100 共 2046个

每页
页面:
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  2. 2
  3. 3
  4. 4
  5. 5

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