“tak”的搜索结果

产品 51 到 100 共 109个

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  1. BX471 hydrochloride

    Catalog No. A21886
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    non-peptide CCR1 antagonist
    BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. 了解更多
  2. Lapaquistat

    Catalog No. A21262
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    cholesterol biosynthesis inhibitor
    Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of TAK-475. Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy. 了解更多
  3. Cenicriviroc

    Catalog No. A13643
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    CCR2/CCR5 抑制剂
    Cenicriviroc是用于治疗HIV感染的实验性候选药物.Cenicriviroc是CCR2和CCR5受体的抑制剂,可使其充当阻止病毒进入人体细胞的进入抑制剂。 了解更多
  4. Mosapride citrate

    Catalog No. A10607
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    5-HT4-receptor 激动剂
    Mosapride citrate起5-HT4受体激动剂和5-HT3受体拮抗剂的作用。 了解更多
  5. HS-243

    Catalog No. A22071
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    transforming growth factor-?beta kinase inhibitor
    HS-243 is an inhibitor of transforming growth factor-?beta kinase. HS-243 can be used in treatment of cancer, malaria, inflammatory and other TAK1-?mediated diseases. 了解更多
  6. Takeda103A

    Catalog No. A22142
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    bovine tubulin oxidation inhibitor
    Takeda103A is a potent GRK2-dependent bovine tubulin oxidation inhibitor. 了解更多
  7. RO6889678

    Catalog No. A22490
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    RO6889678 is an inhibitor of HBV with a complex ADME profile. RO6889678 showed an intracellular enrichment of 78-fold in hepatocytes, with an apparent intrinsic clearance of 5.2 ?l/min per mg protein and uptake and biliary clearances of 2.6 and 1.6 ?l/min per mg protein, respectively. 了解更多
  8. (R)-Viloxazine Hydrochloride

    Catalog No. A22693
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    norepinephrine reuptake inhibitor
    (R)-Viloxazine Hydrochloride is the R-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant. 了解更多
  9. (S)-Viloxazine Hydrochloride

    Catalog No. A22694
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    norepinephrine reuptake inhibitor
    (S)-Viloxazine Hydrochloride is the S-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant. 了解更多
  10. Levophacetoperane hydrochloride

    Catalog No. A20198
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    Levophacetoperane inhibits in vitro in a competitive manner, norepinephrin uptake and dopamine uptake. 了解更多
  11. WAY-213613

    Catalog No. A19992
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    GLT-1/EAAT2 reuptake inhibitor
    WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM EAAT2. 了解更多
  12. Nitroxazepine

    Catalog No. A19888
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    serotonin-norepinephrine reuptake inhibitor
    Nitroxazepine is a tricyclic antidepressant (TCA) for the treatment of depression. Nitroxazepine acts as a serotonin-norepinephrine reuptake inhibitor. 了解更多
  13. SN 6

    Catalog No. A19886
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    NCX inhibitor
    SN 6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor, and inhibits 45Ca2+ uptake by NCX1, NCX2, and NCX3, with IC50s of 2.9, 16, and 8.6 μM, respectively. 了解更多
  14. L 152804

    Catalog No. A19834
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    NPY5-R antagonist
    L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. 了解更多
  15. Tedatioxetine hydrobromide

    Catalog No. A19418
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    triple reuptake inhibitor/5-HT2A/5-HT2C/5-HT3/α1A-adrenergic receptor antagonis
    Tedatioxetine hydrobromide acts as a triple reuptake inhibitor and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. 了解更多
  16. GBR 12935

    Catalog No. A21951
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    dopamine reuptake inhibitor
    GBR 12935 is a potent, and selective dopamine reuptake inhibitor. 了解更多
  17. Eplivanserin mixture

    Catalog No. A21987
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    serotonin reuptake inhibitor/5-HT2A receptor antagonist
    Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, extracted from patent WO 2005/002578 A1. 了解更多
  18. Vanoxerine

    Catalog No. A21922
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    dopamine reuptake inhibitor
    Vanoxerine (GBR-12909) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). 了解更多
  19. Vilazodone D8

    Catalog No. A21876
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    SSR inhibitor / 5-HT1A receptor partial agonist
    Vilazodone D8 is the a deuterium labeled vilazodone, which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. 了解更多
  20. LY2365109 hydrochloride

    Catalog No. A21779
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    GlyT1 inhibitor
    LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a. 了解更多
  21. Dasotraline hydrochloride

    Catalog No. A21684
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    triple reuptake inhibitor
    Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. 了解更多
  22. Dasotraline

    Catalog No. A21618
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    triple reuptake inhibitor
    Dasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. 了解更多
  23. Escitalopram

    Catalog No. A21241
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    selective serotonin reuptake inhibitor (SSRI)
    Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM. 了解更多
  24. Diclofensine hydrochloride

    Catalog No. A20923
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    monoamine reuptake inhibitor
    Diclofensine hydrochloride (Ro-8-4650 hydrochloride) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively. 了解更多
  25. VU 0240551

    Catalog No. A20854
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    KCC2 inhibitor
    VU 0240551 is a small molecule inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2-overexpressing cells). 了解更多
  26. Escitalopram oxalate

    Catalog No. A16533
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    Serotonin reuptake inhibitor
    Escitalopram oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM. 了解更多
  27. SPD-473 citrate

    Catalog No. A12617
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    serotonin/dopamine/norepinephrine reuptake inhibitior
    SPD-473 citrate is a serotonin/dopamine/norepinephrine reuptake inhibitior. 了解更多
  28. GPI-1046

    Catalog No. A13015
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    GPI-1046 is a immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core. 了解更多
  29. NBTGR

    Catalog No. A13489
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    Nucleoside transport inhibitor
    NBTGR (p-Nitrobenzylthioguanosine) is a potent inhibitor of nucleoside transport; inhibits adenosine uptake with a Ki of 70 nM. 了解更多
  30. 2-NBDG

    Catalog No. A18859
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    2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose, but not L-glucose or sucrose, in E. coli.1 It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies. 了解更多
  31. DMT1 blocker 2

    Catalog No. A18999
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    DMT1 inhibitor
    DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo. 了解更多
  32. DMT1 blocker 1

    Catalog No. A19005
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    DMT1 blocker
    DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo. 了解更多
  33. Amezinium methylsulfate

    Catalog No. A18103
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    norepinephrine reuptake inhibitor
    Amezinium Metilsulfate, also known as Regulton and LU-1631, is a norepinephrine reuptake inhibitor which exclusively affects postganglionic sympathetic neurons. Amezinium Metilsulfate is used to treat hypotension. 了解更多
  34. Paroxetine mesylate

    Catalog No. A17566
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    serotonin uptake inhibitor
    Paroxetine Mesylate is a serotonin uptake inhibitor that is effective in the treatment of depression. 了解更多
  35. Bentiromide

    Catalog No. A17390
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    Bentiromide is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is given by mouth as a noninvasive test. The amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. 了解更多
  36. Amitraz

    Catalog No. A17266
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    Amitraz, also known as Mitaban and Taktic, is an alpha-adrenergic receptor agonist and MAO inhibitor used as an insecticide in prevention of flea and tick infections. It prevents prostaglandin synthesis and may inhibit beta-cell insulin release. 了解更多
  37. Takinib

    Catalog No. A16960
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    TAK1 抑制剂
    Takinib是一种选择性的TAK1抑制剂,在类风湿性关节炎和转移性乳腺癌的细胞模型中,TNF-α刺激后可诱导细胞凋亡。 了解更多
  38. FUR E.Coli

    Catalog No. AP2037
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    Ferric Uptake Regulator E.Coli Recombinant 了解更多
  39. YL-0919

    Catalog No. A16337
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    5-HT1A receptor 激动剂/serotonin reuptake 抑制剂
    YL0919,具有5-HT1A受体激动剂和选择性5-羟色胺再摄取抑制剂双重活性的新型抗抑郁候选药物,YL-0919抑制5-HT被大鼠大脑皮层突触小体和人重组细胞摄取的IC50值为1.78±0.34 nM和1.93±0.18 nM。 了解更多
  40. Tiagabine hydrochloride

    Catalog No. A16135
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    GABA reuptake 抑制剂
    Tiagabine hydrochloride是一种抗惊厥药。该药物还用于治疗惊恐症,还有其他一些抗惊厥药。 了解更多
  41. Tiagabine

    Catalog No. A13198
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    GABA reuptake 抑制剂
    Tiagabine是一种选择性γ-氨基丁酸(gaba)再摄取抑制剂。 了解更多
  42. MCI-225

    Catalog No. A15502
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    NA reuptake 抑制剂
    MCI-225是具有5-HT3受体拮抗作用的选择性NA再摄取抑制剂。 了解更多
  43. Desvenlafaxine succinate hydrate

    Catalog No. A15491
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    serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂
    Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂,Ki值分别为40.2 nM和558.4 nM 了解更多
  44. Azaphen dihydrochloride monohydrate

    Catalog No. A15009
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    serotonin reuptake 抑制剂
    Azaphen dihydrochloride monohydrate是5-羟色胺再摄取的有效抑制剂。 了解更多
  45. Phenylpiracetam

    Catalog No. A15211
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    Dopamine reuptake 抑制剂
    Phenylpiracetam是促智药物吡乙酰胺的苯基化衍生物。它被用作促智药物,效力比吡乙酰胺高30-60倍。 了解更多
  46. NG25

    Catalog No. A15185
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    TAK1/MAP4K2 抑制剂
    NG25和TAK1抑制TLR7和TLR9激动剂激活IKK,并阻止Gen2.2细胞中这些配体诱导的1型IFN分泌。 了解更多
  47. Bitopertin (R enantiomer)

    Catalog No. A15022
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    Glycine reuptake 抑制剂
    Bitopertin (R enantiomer)是一种有效的非竞争性甘氨酸再摄取抑制剂(GlyT1)。 了解更多
  48. Bitopertin

    Catalog No. A15021
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    Glycine reuptake 抑制剂
    Bitopertin是一种有效的非竞争性甘氨酸再摄取抑制剂(GlyT1)。 了解更多
  49. Nisoxetine hydrochloride

    Catalog No. A13418
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    Noradrenalin re-uptake 抑制剂
    Nisoxetine hydrochloride是去甲肾上腺素转运蛋白的选择性强抑制剂,对一系列其他神经递质受体几乎没有或没有亲和力。Nisoxetine hydrochloride是SLC6A2的抑制剂。 了解更多
  50. Norfluoxetine

    Catalog No. A13458
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    serotonin uptake 抑制剂
    Norfluoxetine是抗抑郁药氟西汀的活性代谢物,抑制5-羟色胺的摄取,pKi值为7.35.1氟西汀的S-对映体的5-羟色胺再摄取阻断能力是R-对映体的20倍(pKis分别为7.86和6.51)。 了解更多

产品 51 到 100 共 109个

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