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Nomegestrol acetate
Catalog No. A21829 progesterone receptor agonistNomegestrol acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors. 了解更多 -
RSV604 racemate
Catalog No. A21817 RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer. 了解更多 -
CP-640186 hydrochloride
Catalog No. A21808 ACC inhibitorCP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. 了解更多 -
Mavoglurant racemate
Catalog No. A21799 mGlu5 receptor antagonistMavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. 了解更多 -
Rusalatide acetate
Catalog No. A21791 regenerative peptideRusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. 了解更多 -
Nevanimibe hydrochloride
Catalog No. A21767 ACAT1 inhibitorNevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. 了解更多 -
BAY 73-6691 racemate
Catalog No. A21745 PDE9 inhibitorBAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1. 了解更多 -
GSK2807 Trifluoroacetate
Catalog No. A21731 SMYD3 inhibitorGSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM. 了解更多 -
N8-Acetylspermidine dihydrochloride
Catalog No. A21720 N8-Acetylspermidine dihydrochloride is a polyamine. 了解更多 -
Taranabant racemate
Catalog No. A21699 CB1 antagonist/inverse agonistTaranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor extracted from patent WO 2004048317 A1. 了解更多 -
(Rac)-Antineoplaston A10
Catalog No. A21689 Ras inhibitor(rac)-Antineoplaston A10 is the racemate of Antineoplaston A10. Antineoplaston A10 is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. 了解更多 -
3-Methoxytyramine
Catalog No. A21676 neuromodulator3-Methoxytyramine, a well known extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator. 了解更多 -
nor-NOHA acetate
Catalog No. A21673 Arginase inhibitornor-NOHA acetate is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. 了解更多 -
Nanatinostat
Catalog No. A21625 HDAC inhibitorNanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM. 了解更多 -
Acetoacetic acid sodium salt
Catalog No. A21621 Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. 了解更多 -
INCB054329 Racemate
Catalog No. A21609 -
(±)-BAY-1251152
Catalog No. A21564 PTEF/CDK9 inhibitor(±)-BAY-1251152 is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. 了解更多 -
Varenicline Hydrochloride
Catalog No. A21539 α4β2 nAChR partial agonistVarenicline Hydrochloride (CP 526555 hydrochloride) is a high affinity, selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist and full α7 nAChR agonist. 了解更多 -
Finasteride acetate
Catalog No. A21537 testosterone 5-alpha-reductase inhibitorFinasteride (acetate) is an orally active testosterone 5-alpha-reductase inhibitor. 了解更多 -
VU 0238429
Catalog No. A21519 positive allosteric modulatorVU 0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5), with an EC50 of 1.16 μM. 了解更多 -
GDC-0927 Racemate
Catalog No. A21507 estrogen receptor degraderGDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. 了解更多 -
Litronesib Racemate
Catalog No. A21498 kinesin Eg5 inhibitorLitronesib (Racemate) is the racemate of litronesib. Litronesib is a selective, allosteric inhibitor of kinesin Eg5. 了解更多 -
L 888607 Racemate
Catalog No. A21482 DP1 antagonistL 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively. 了解更多 -
PF-05175157
Catalog No. A21460 ACC inhibitorPF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. 了解更多 -
PNU-282987 S enantiomer free base
Catalog No. A21459 PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist. 了解更多 -
(±)-Ibipinabant
Catalog No. A21439 CB-1 receptor antagonist(±)-Ibipinabant ((±)-SLV319) is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM. 了解更多 -
Naspm trihydrochloride
Catalog No. A21437 CP-AMPA receptors antagonistNaspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多 -
ADH-1 trifluoroacetate
Catalog No. A21417 N-cadherin antagonistADH-1 trifluoroacetate is an N-cadherin antagonist, which inhibits N-cadherin mediated cell adhesion. 了解更多 -
ATN-161 trifluoroacetate salt
Catalog No. A21412 integrin α5β1 antagonistATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. 了解更多 -
Peliglitazar racemate
Catalog No. A21411 dual α/γ PPAR activatorPeliglitazar racemate is the racemate of Peliglitazar. Peliglitazar is a novel dual α/γ PPAR activator. 了解更多 -
Sch-42495 racemate
Catalog No. A21408 NEP inhibitorSch-42495 racemate is the racemate of Sch-42495. Sch-42495 is a novel neutral metalloendopeptidase (NEP) inhibitor. Sch-42495 is the orally active ethylester prodrug of SCH 42354. 了解更多 -
Plecanatide acetate
Catalog No. A21393 GC-C receptor agonistPlecanatide acetate is a guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis. 了解更多 -
(Rac)-Nedisertib
Catalog No. A21383 DNA-PK inhibitor(Rac)-Nedisertib ((Rac)-M3814) is a racemate of Nedisertib, a potent DNA-PK inhibitor, with an IC50 of <3 nM. 了解更多 -
DHMEQ racemate
Catalog No. A21379 NF-κB inhibitorDHMEQ racemate is a NF-κB inhibitor. DHMEQ racemate is less active than (-)-DHMEQ. 了解更多 -
Exendin-4 Acetate
Catalog No. A21378 glucagon-like peptide-1 receptor agonistExendin-4 Acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. 了解更多 -
(Rac)-PT2399
Catalog No. A21376 HIF-2α inhibitor(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM. 了解更多 -
Raphin1 acetate
Catalog No. A21373 PPP1R15B inhibitorRaphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). 了解更多 -
PhiKan 083 hydrochloride
Catalog No. A21372 PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells. 了解更多 -
AZD-5991 S-enantiomer
Catalog No. A21361 Mcl-1 inhibitorAZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay. 了解更多 -
AZD-5991 Racemate
Catalog No. A21357 Mcl-1 inhibitorAZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is a Mcl-1 inhibitor with an IC50 of <3 nM in FRET assay. 了解更多 -
Rasagiline 13C3 mesylate racemic
Catalog No. A21350 Monoamine oxidase inhibitorRasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. 了解更多 -
SB290157 trifluoroacetate
Catalog No. A21347 C3a receptor antagonistSB290157 trifluoroacetate is a potent and selective C3a receptor antagonist with an IC50 of 200 nM. 了解更多 -
β-Secretase Inhibitor IV
Catalog No. A21346 BACE-1 inhibitorβ-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. 了解更多
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