Pim
Catalog No. | Inhibitor Name | Pim1 | Pim2 | Pim3 | Other |
---|---|---|---|---|---|
A10838 | SGI-1776 free base | *** | * | * | FLT3 |
A11945 | SMI-4a | ** | |||
A14275 | CX-6258 HCl | *** | ** | ** | |
A13203 | AZD1208 | **** | *** | **** | |
A11967 | TCS PIM-1 4a | ** | * | ||
A12896 | CX-6258 | *** | ** | ** | |
A15368 | PIM-1 Inhibitor 2 | * | |||
A15369 | TCS PIM-1 1 | * |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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LGB-321 HCl
Catalog No. A14420 Pan-PIM kinase 抑制剂LGB-321 HCl是一种有效且选择性的PIM激酶竞争性小分子抑制剂(Pan-PIM激酶抑制剂)。 了解更多 -
CX-6258 hydrochloride hydrate
Catalog No. A15055 Pim 抑制剂CX-6258 hydrochloride hydrate是一种有效的,口服有效的Pim 1/2/3激酶(IC50 = 5 nM/25 nM/16 nM)抑制剂,具有出色的生化效能和激酶选择性。 了解更多 -
CX-6258 HCl
Catalog No. A14275 Pan-PIM kinase 抑制剂CX-6258 HCl是一种有效的口服泛Pim激酶抑制剂,对Pim1,Pim2和Pim3的IC50为5 nM,25 nM和16 nM。 了解更多