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使用 'FXR' 作为标签的产品

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GW4064

Catalog No. A11141
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FXR 激动剂

GW4064是选择性的非甾体类法尼醇X受体（FXR）激动剂（EC50 = 15 nM）。了解更多

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- Dong-Hyun Kim, .et al. The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD, Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132
- Takae K, .et al. Evidence for the involvement of FXR signaling in ovarian granulosa cell function, J Reprod Dev, 2018, Nov 16 PMID: 30449821
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Lithocholic acid

Catalog No. A12547
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FXR 激动剂

Lithocholic acid是胆汁酸，用作去污剂以溶解脂肪以供吸收。了解更多

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Obeticholic Acid

Catalog No. A13866
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FXR 激动剂

Obeticholic Acid是一种有效的选择性法呢类X受体（FXR）激动剂，EC50为99 nM。了解更多

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- Tomasz Kostrzewski, .et al. A Microphysiological System for Studying Nonalcoholic Steatohepatitis, Hepatol Commun, 2019, 13 November
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T0901317

Catalog No. A12652
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LXR/FXR 激动剂

T0901317是有效的，高亲和力的肝X受体（LXR）激动剂（EC50~50 nM，LXR-β和LXR-β的Kd值分别为7和22 nM）。了解更多

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- Tian Yongsong, .et al. Tritium hydrogen-isotope exchange with electron-poor tertiary benzenesulfonamide moiety; application in late-stage labeling of T0901317, J Labelled Comp Radiopharm, 2022, Feb;65(2):36-44 PMID: 34957593
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WAY-362450

Catalog No. A11186
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FXR 激动剂

WAY-362450是一种高效，选择性和口服可生物利用的法呢类X受体（FXR）激动剂（EC50：4 nM，eff = 149％）。了解更多

Product Citations (2)

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- Dong-Hyun Kim, .et al. The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD, Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132
- Dong-Hyun Kim, .et al. Src-mediated crosstalk between FXR and YAP protects against renal fibrosis, FASEB J, 2019, Jul 12:fj201900325R PMID: 31298930

Adooq Bioscience

使用 'FXR' 作为标签的产品

GW4064

Lithocholic acid

Obeticholic Acid

T0901317

WAY-362450

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