5-HT Receptors

16 个项目

每页

设置降序顺序
  1. Vilazodone

    Catalog No. A11116
    Quick View
    Serotonin reuptake 抑制剂
    Vilazodone充当5-羟色胺再摄取抑制剂(IC50 = 0.5 nM)和5-HT1A受体部分激动剂(IC50 = 0.2 nM; IA =?60-70%)。 了解更多
  2. Sibutramine hydrochloride

    Catalog No. A12397
    Quick View
    SNR 抑制剂
    Sibutramine hydrochloride是5-HT和去甲肾上腺素再摄取抑制剂(SNRI)。 了解更多
  3. Levomilnacipran HCl

    Catalog No. A14391
    Quick View
    serotonin/NE reuptake 抑制剂
    Levomilnacipran HCl是一种选择性的5-羟色胺和去甲肾上腺素再摄取抑制剂。 了解更多
  4. Edivoxetine HCl

    Catalog No. A13865
    Quick View
    norepinephrine reuptake 抑制剂
    Edivoxetine HCl是一种选择性去甲肾上腺素再摄取抑制剂。 了解更多
  5. Norfluoxetine

    Catalog No. A13458
    Quick View
    serotonin uptake 抑制剂
    Norfluoxetine是抗抑郁药氟西汀的活性代谢物,抑制5-羟色胺的摄取,pKi值为7.35.1氟西汀的S-对映体的5-羟色胺再摄取阻断能力是R-对映体的20倍(pKis分别为7.86和6.51)。 了解更多
  6. Atomoxetine HCl

    Catalog No. A13424
    Quick View
    norepinephrine (NE) transporter 抑制剂
    Atomoxetine HCl是SLC6A2的一种竞争性特异性抑制剂,同时在大鼠下丘脑突触体中显示出微弱的ST和DAT抑制作用。 了解更多
  7. Asenapine HCl

    Catalog No. A15002
    Quick View
    adrenergic receptor/5-HT receptor 抑制剂
    Asenapine hydrochloride抑制肾上腺素能受体(α1,α2A,α2B,α2C)的Ki为0.25-1.2 nM,还抑制5-HT受体(1A,1B,2A,2B,2C,5A,6、7),Ki为0.03- 4.0 nM。 了解更多
  8. Desvenlafaxine succinate hydrate

    Catalog No. A15491
    Quick View
    serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂
    Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂,Ki值分别为40.2 nM和558.4 nM 了解更多
  9. YL-0919

    Catalog No. A16337
    Quick View
    5-HT1A receptor 激动剂/serotonin reuptake 抑制剂
    YL0919,具有5-HT1A受体激动剂和选择性5-羟色胺再摄取抑制剂双重活性的新型抗抑郁候选药物,YL-0919抑制5-HT被大鼠大脑皮层突触小体和人重组细胞摄取的IC50值为1.78±0.34 nM和1.93±0.18 nM。 了解更多
  10. Eucalyptol

    Catalog No. A15662
    Quick View
    5-HT3 receptor 抑制剂
    Eucalyptol是一种在桉树和其他植物中发现的双环单萜。它是5-HT3受体,钾通道,TNF-α的抑制剂。和IL-1β。 了解更多
  11. Nefazodone hydrochloride

    Catalog No. A17622
    Quick View
    5-HT2 receptors inhibitor
    Nefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多
  12. Flopropione

    Catalog No. A16550
    Quick View
    5-HT1A receptor antagonist/COMT inhibitor
    Flopropione是5-HT1A受体拮抗剂,也是儿茶酚-邻甲基转移酶(COMT)抑制剂。 了解更多
  13. MHP 133

    Catalog No. A20058
    Quick View
    AChE /M1/M2/5HT4/I2 inhibitor
    MHP 133 is a drug with multiple CNS targets, and inhibits acetylcholinesterase (AChE) with Ki of 69 μM; also active against muscarinic M1 and M2 receptors, serotonin 5HT4 receptors, and imidazole I2 receptors. 了解更多
  14. Vortioxetine

    Catalog No. A21266
    Quick View
    5-HT1A/5-HT1B/5-HT3A/5-HT7 receptor/SERT inhibitor
    Vortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. 了解更多
  15. Vilazodone D8

    Catalog No. A21876
    Quick View
    SSR inhibitor / 5-HT1A receptor partial agonist
    Vilazodone D8 is the a deuterium labeled vilazodone, which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. 了解更多
  16. Eplivanserin mixture

    Catalog No. A21987
    Quick View
    serotonin reuptake inhibitor/5-HT2A receptor antagonist
    Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, extracted from patent WO 2005/002578 A1. 了解更多

16 个项目

每页

设置降序顺序
Rewards