Nutlin-3

目录号: A10657

Mdm2 拮抗剂

Nutlin-3

Nutlin-3 Chemical Structure

CAS NO. 548472-68-0

Nutlin-3是一种有效的,选择性Mdm2(它自身和p53的环指依赖性泛素蛋白连接酶)拮抗剂,是有效的凋亡诱导剂。

库存: 现货

规格 价格 数量
5 mg
¥ 455.00
25 mg
¥ 1,400.00
50 mg
¥ 2,520.00
100 mg
¥ 3,920.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Nutlin-3是一种有效的,选择性Mdm2(它自身和p53的环指依赖性泛素蛋白连接酶)拮抗剂,是有效的凋亡诱导剂。
In vitro DMSO 87 mg/mL (149.61 mM)
Water Insoluble
Ethanol 26 mg/mL (44.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.2 mL 85.98 mL 171.97 mL
0.5 mM 3.44 mL 17.2 mL 34.39 mL
1 mM 1.72 mL 8.6 mL 17.2 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10657
作用机制 Antagonist (拮抗剂)
M. Wt 581.5
Formula C30H30Cl2N4O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 548472-68-0
Synonyms Nutlin3
SMILES CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

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