Ki8751

目录号: A10502

VEGFR-2 抑制剂

Ki8751

Ki8751 Chemical Structure

CAS NO. 228559-41-9

ki8751是一种细胞可渗透的喹啉氧基苯基脲化合物,在基于细胞和无细胞的检测中起Flk-1 (VEGFR-2)选择性抑制剂的作用。

库存: 现货

规格 价格 数量
5 mg
¥ 350.00
10 mg
¥ 525.00
50 mg
¥ 2,100.00
100 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 560.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

ki8751是一种细胞可渗透的喹啉氧基苯基脲化合物,在基于细胞和无细胞的检测中起Flk-1 (VEGFR-2)选择性抑制剂的作用。
Targets
Target Value
VEGFR2IC50: 0.9nM
c-KitIC50: 40nM
PDGFRαIC50: 67nM
FGFR2IC50: 170nM
EGFRIC50: >10μM
HGFRIC50: >10μM
Insulin ReceptorIC50: >10μM
In vitro (25°C) DMSO 46 mg/mL (97.99 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+corn oil 2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.52 mL 213.04 mL
0.5 mM 4.26 mL 21.3 mL 42.61 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10502
作用机制 Inhibitor (抑制剂)
M. Wt 469.4
Formula C24H18F3N3O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 228559-41-9
Synonyms Ki-8751
SMILES COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F

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