“angiotensin receptors”的搜索结果
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Opioid Receptors 激动剂
BRL 52537 hydrochloride是一种高度选择性和有效的κ阿片类激动剂(Ki = 0.24 nM)。比吗啡强25倍。
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β3-adrenergic receptors 激动剂
BRL 37344 Na Salt是具有脂解活性的β3-AR(β3-肾上腺素能受体)选择性激动剂。
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β-adrenergic receptors 激动剂
Cimaterol是β的有效激动剂;肾上腺素能受体(人β的pEC50 = 8.13、8.78和6.62;1β,2β和3β)。
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5-HT2C receptor agonist
CP-809101 is a potent and selective 5-HT2C receptor agonist with pEC50 of 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors respectively.
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A3 adenosine receptor agonist
AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors.
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mGluRs M3 agonist
L-APB is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively.
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group II (mGlu2/3) receptor agonist
Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively.
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D3 receptor and D2 receptor partial agonist
Cariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
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5-HT1B/1D receptors agonist
Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively.
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peripheral oxytocin receptors agonist
Carbetocin (Lonactene; Duratocin) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth; an agonist at peripheral oxytocin receptors.
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5-HT1A/5-HT1B receptors agonist
RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.
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group III mGluR receptors agonist
O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2.
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opioid receptors agonist
DPI-3290 (Org 41793) is a potent and specific opioid receptors agonist with Ki values of 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively.
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GPR119 receptors agonist
PSN632408 is an optimized agonist of GPR119 receptors that shows similar potency to OEA at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 5.6 and 7.9 uM, respectively.
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