你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
搜索结果：“jwh 250”

“jwh 250”的搜索结果

Quick View
ORM-10103

Catalog No. A18404
Quick View

添加到收藏
Na+/Ca2+ exchanger (NCX) 抑制剂

ORM-10103 is a specific inhibitor of the Na+/Ca2+ exchanger (NCX), which decreases the NCX current with estimated IC50s of 55 and 67 nM at -80 and at 20 mV, respectively. 了解更多

Bulk Inquiry
Quick View
Azaphen dihydrochloride monohydrate

Catalog No. A15009
Quick View

添加到收藏
serotonin reuptake 抑制剂

Azaphen dihydrochloride monohydrate是5-羟色胺再摄取的有效抑制剂。了解更多

Bulk Inquiry
Quick View
Thapsigargin

Catalog No. A14007
添加到收藏
SERCA ATPase 抑制剂

Thapsigargin是在Thapsia garganica的根中发现的一种细胞可渗透的倍半萜烯内酯。它是肿瘤的启动子，可通过抑制肌浆/内质网Ca2+ -ATPase（SERCA，IC50 = 30 nM）诱导细胞内储存的Ca2+释放，而不会水解肌醇磷脂。了解更多

Bulk Inquiry
Quick View
Oligomycin

Catalog No. A14000
添加到收藏
ATP synthase 抑制剂

Oligomycin是一种大环内酯类化合物，可作为线粒体ATP合酶的特异性抑制剂并阻止氧化磷酸化作用。了解更多

Bulk Inquiry
Quick View
GZ-793A

Catalog No. A13569
Quick View

添加到收藏
VMAT2 抑制剂

GZ-793A是囊泡单胺转运蛋白2 (VMAT2)的选择性抑制剂，它将单胺神经递质从细胞胞质溶胶转运到突触小泡中。了解更多

Bulk Inquiry
Quick View
Melittin

Catalog No. A13912
Quick View

添加到收藏
Na+/K+ ATPase 抑制剂

Melittin是一种Na+/K+ ATPase抑制剂。它抑制Gs并刺激Gi活性。它抑制蛋白激酶C和依赖cAMP的蛋白激酶。了解更多

Bulk Inquiry Free Sample
Quick View
Procainamide HCl

Catalog No. A14240
Quick View

添加到收藏
Sodium channel blocker/DNMT 抑制剂

Procainamide HCl是钠通道阻滞剂，又是DNA甲基转移酶抑制剂。了解更多

Bulk Inquiry
Quick View
HC-030031

Catalog No. A13278
Quick View

添加到收藏
TRPA1 抑制剂

HC-030031是选择性TRPA1阻滞剂，可拮抗AITC和福尔马林诱导的TRPA1介导的钙内流（IC50分别为6.2和5.3 uM）。了解更多

Bulk Inquiry Free Sample
Quick View
CFTR-Inhibitor-II

Catalog No. A13723
Quick View

添加到收藏
CFTR 抑制剂

CFTR inhibitor II,也称为GlyH-101，是一种甘氨酸酰肼，可选择性和可逆地阻断CFTR通道（Ki = 4.3 uM）。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
Quick View
KB-R7943 mesylate

Catalog No. A11933
Quick View

添加到收藏
Na+/Ca2+ Exchanger 抑制剂

KB-R7943 mesylate是一种在表达NCX1的细胞中具有Na+/Ca2+交换反向模式的细胞渗透性强效选择性NCKX抑制剂。了解更多

Bulk Inquiry
Quick View
Canagliflozin

Catalog No. A11100
Quick View

添加到收藏
SGLT2 抑制剂

canagliflozin是2型亚钠葡萄糖转运蛋白（SGLT2）的抑制剂,作用于hSGLT2，无细胞试验中IC50为2.2 nM，比作用于hSGLT1选择性高413倍。了解更多

Product Citations (2)

Bulk Inquiry Free Sample
- David Papadopoli, .et al. Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin, Neoplasia, 2021, Apr;23(4):391-399 PMID: 33784591
- Angelopoulou A, .et al. Canagliflozin-loaded magnetic nanoparticles as potential treatment of hypoxic tumors in combination with radiotherapy, Nanomedicine, 2018, Oct;13(19):2435-2454 PMID: 30311542
Quick View
Dapagliflozin (BMS512148)

Catalog No. A10285
Quick View

添加到收藏
SGLT2 抑制剂

Dapagliflozin (BMS512148)抑制钠-葡萄糖转运蛋白（SGLT2）的亚型2，后者负责肾脏中至少90％的葡萄糖重吸收。了解更多

Product Citations (5)

Bulk Inquiry Free Sample
- David Papadopoli, .et al. Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin, Neoplasia, 2021, Apr;23(4):391-399 PMID: 33784591
- Neil Tanday, .et al. Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance, Biochem Pharmacol, 2020, Jul;177:114009 PMID: 32360307
- Subramaniam M, .et al. Comparison of Intestinal Glucose Flux and Electrogenic Current Demonstrates Two Absorptive Pathways in Pig and One in Nile Tilapia and Rainbow Trout, Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628
- Marina Subramaniam, .et al. Sigmoidal kinetics define porcine intestinal segregation of electrogenic monosaccharide transport systems as having multiple transporter population involvement, Physiol Rep, 2019, May; 7(9): e14090 PMID: 31062524
- Angelopoulou A, .et al. Magnetic Nanoparticles for the Delivery of Dapagliflozin to Hypoxic Tumors: Physicochemical Characterization and Cell Studies, AAPS PharmSciTech, 2018, Feb;19(2):621-633 PMID: 8924948
Quick View
Vinpocetine

Catalog No. A11602
Quick View

添加到收藏
PDE1 抑制剂

Vinpocetine是一种Ca2+钙调蛋白依赖性磷酸二酯酶I（PDE1）抑制剂。了解更多

Bulk Inquiry
Quick View
Imipramine Hydrochloride

Catalog No. A13410
Quick View

添加到收藏
Serotonin transporter 抑制剂

Imipramine Hydrochloride是一种三环抗抑郁药。抑制血清素和去甲肾上腺素转运蛋白，但对多巴胺转运蛋白几乎没有影响。了解更多

Bulk Inquiry
Quick View
CHC

Catalog No. A13372
Quick View

添加到收藏
MCT 抑制剂

CHC是单羧酸转运（MCT）抑制剂。在神经胶质瘤中具有抗肿瘤和抗血管生成活性；降低U251细胞的糖酵解代谢，迁移和侵袭。了解更多

Bulk Inquiry Free Sample
Quick View
Nimodipine

Catalog No. A10645
Quick View

添加到收藏
Calcium Channel 抑制剂

Nimodipine是一种L型Ca2+通道阻滞剂。了解更多

Bulk Inquiry Free Sample
Quick View
Omeprazole

Catalog No. A10672
Quick View

添加到收藏
ATPase 抑制剂

Omeprazole是一种可透过细胞的选择性质子泵抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Ouabain

Catalog No. A12755
添加到收藏
a-K-ATPase 抑制剂

Ouabain是一种选择性的Na+，K+-ATPase抑制剂。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Paul Mark Medina, .et al. Revealing the anticancer potential of candidate drugs in vivo using Caenorhabditis elegans mutant strains, Transl Oncol, 2021, Jan;14(1):100940 PMID: 33221682

联系我们

Not your Region? View all Distributors

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.