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搜索结果：“Ligand-gated Ion Channels”

“Ligand-gated Ion Channels”的搜索结果

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FR 167653 free base

Catalog No. A21110
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p38 MAPK inhibitor

FR 167653 free base, an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. 了解更多

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ERK-IN-1

Catalog No. A19080
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RAF/ERK1/2 inhibitor

ERK-IN-1 (compound B) is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. 了解更多

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LUT014

Catalog No. A19449
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B-Raf inhibitor

LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 . 了解更多

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PNRI-299

Catalog No. A16305
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AP-1 transcription 抑制剂

PNRI-299是一种选择性AP-1转录抑制剂，IC50为20 uM，不影响NF-κB转录（最高200μM）或硫氧还蛋白（最高200μM）。了解更多

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SR 11302

Catalog No. A14950
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AP-1 transcription factor 抑制剂

SR 11302，活化蛋白1（AP-1）转录因子活性的抑制剂，在体内表现出抗肿瘤作用。了解更多

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