“bone morphogenetic proteins bmp”的搜索结果

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  1. p53 and MDM2 proteins-interaction-inhibitor racemic

    Catalog No. A15202
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    p53-MDM2 interaction 抑制剂
    p53和MDM2蛋白相互作用抑制剂消旋体是p53和MDM2蛋白之间相互作用的抑制剂。 了解更多
  2. p53 and MDM2 proteins-interaction-inhibitor chiral

    Catalog No. A15201
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    p53-MDM2 interaction 抑制剂
    p53和MDM2蛋白相互作用抑制剂手性是p53和MDM2蛋白之间相互作用的抑制剂。 了解更多
  3. LDN193189 Tetrahydrochloride

    Catalog No. A21881
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    BMP type I receptor inhibitor
    LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50??500 nM). 了解更多
  4. Dantrolene sodium

    Catalog No. A17644
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    Calcium channel proteins inhibitor
    Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. 了解更多
  5. Dorsomorphin 2HCl

    Catalog No. A13720
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    BMP 抑制剂
    Dorsomorphin 2HCl (BML-275)是BMP信号传导的选择性小分子抑制剂,可促进胚胎干细胞的心肌发生。Dorsomorphin通过抑制骨形态发生蛋白信号转导逆转乳腺癌起始细胞的间质表型。 了解更多
  6. K02288

    Catalog No. A14311
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    BMP 抑制剂
    K02288是一种有效的选择性I型BMP受体抑制剂,对ALK2,ALK1和ALK6的IC50为1.1、1.8、6.4 nM。 了解更多
  7. ML347

    Catalog No. A14298
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    BMP receptor 抑制剂
    ML347是一种选择性BMP受体抑制剂。 了解更多
  8. LDN-212854

    Catalog No. A12821
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    BMP receptor 抑制剂
    LDN-212854是一种ALK2偏爱的BMP I型受体激酶抑制剂。 了解更多
  9. DMH-1

    Catalog No. A12820
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    ALK2 抑制剂
    DMH-1是骨形态发生蛋白(BMP)ALK2受体的选择性抑制剂(IC50 = 108 nM)。 了解更多
  10. Zoledronic Acid

    Catalog No. A11010
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    osteoclastic bone resorption 抑制剂
    Zoledronic acid, 破骨细胞抑制剂,通过抑制甲羟戊酸途径诱导破骨细胞凋亡。 了解更多
  11. TAS-116

    Catalog No. A20987
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    HSP90??/HSP90?? inhibitor
    TAS-116 is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor (Kis of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94. TAS-116 demonstrates less ocular toxicity. 了解更多
  12. Leptomycin B

    Catalog No. A20985
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    nuclear export receptor CRM1 inhibitor
    Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle. 了解更多
  13. Beclabuvir

    Catalog No. A21511
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    HCV NS5B RNA-dependent RNA polymerase inhibitor
    Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. 了解更多
  14. Mutant IDH1-IN-2

    Catalog No. A21339
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    IDH inhibitor
    Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay. 了解更多
  15. Nicodicosapent

    Catalog No. A20841
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    SREBP inhibitor
    Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1. 了解更多
  16. BMS-986158

    Catalog No. A19442
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    Bromodomain inhibitor
    BMS-986158 is an inhibitor of the bromodomain and extra-terminal (BET) proteins. 了解更多
  17. CCG-63808

    Catalog No. A11374
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    RGS inhibitor
    CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. 了解更多
  18. (S)-JQ-35

    Catalog No. A18730
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    BET inhibitor
    (S)-JQ-35 (TEN-010) is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins with potential antineoplastic activity. 了解更多
  19. KBU2046

    Catalog No. A18750
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    cell motility and cell invasion inhibitor
    KBU2046 is an oral, highly selective inhibitor of cell motility and cell invasion in vitro. KBU2046 binds chaperone heterocomplexes, selectively alters binding of client proteins that regulate motility, and lacks all of the hallmarks of classical HSP90 inhibitors. KBU2046 inhibits cancer metastasis and prolongs life. 了解更多
  20. Promazine hydrochloride

    Catalog No. A17638
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    D2DR inhibitor
    Promazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多
  21. Mcl1-IN-1

    Catalog No. A18368
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    Mcl-1 inhibitor
    Mcl1-IN-1 is a potent and selective inhibitor of the apoptosis regulating proteins Mcl-1. 了解更多
  22. NBMPR

    Catalog No. A13701
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    ENT1 抑制剂
    NBMPR是一种核苷类似物,可竞争性抑制平衡的核苷转运蛋白1(大鼠和人的Kd = 0.1-1.0 nM,IC50s = 4.6和3.6 nM)。 了解更多
  23. LDN193189

    Catalog No. A11205
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    ALK 抑制剂
    LDN193189是一种高效的小分子BMP抑制剂,可抑制BMP I型受体ALK2(IC50=5 nM),ALK3(IC50=30 nM)和ALK6(TGFβ1/BMP信号转导)以及随后的SMAD磷酸化。 了解更多
  24. GW788388

    Catalog No. A11083
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    TGF-beta/Smad 抑制剂
    GW788388是有效的,口服活性的,选择性的转化生长因子β受体I(TGF-βR1)(激活素受体样激酶5,ALK5)抑制剂,无细胞试验中IC50为18 nM,也抑制TGF-βII型受体和activin II型受体活性,但不抑制BMP II型受体。 了解更多

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